ID   W8BKY3_CERCA            Unreviewed;       612 AA.
AC   W8BKY3;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   03-MAY-2023, entry version 25.
DE   RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
OS   Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC   Tephritidae; Ceratitis; Ceratitis.
OX   NCBI_TaxID=7213 {ECO:0000313|EMBL:JAB97643.1};
RN   [1] {ECO:0000313|EMBL:JAB97643.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Geib S.;
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:JAB97643.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA   Calla B., Hall B., Hou S., Geib S.M.;
RT   "A genomic perspective to assessing quality of mass-reared SIT flies used
RT   in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT   California.";
RL   BMC Genomics 15:98-98(2014).
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DR   EMBL; GAMC01008912; JAB97643.1; -; mRNA.
DR   AlphaFoldDB; W8BKY3; -.
DR   GO; GO:0008190; F:eukaryotic initiation factor 4E binding; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0045727; P:positive regulation of translation; IEA:InterPro.
DR   CDD; cd22454; KH-I_Mextli_like; 1.
DR   Gene3D; 1.25.40.180; -; 1.
DR   Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR040160; Mxt.
DR   PANTHER; PTHR20849:SF2; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN MEXTLI; 1.
DR   PANTHER; PTHR20849; UNCHARACTERIZED; 1.
DR   Pfam; PF00013; KH_1; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR   PROSITE; PS50084; KH_TYPE_1; 1.
PE   2: Evidence at transcript level;
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT   DOMAIN          197..268
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|SMART:SM00322"
FT   REGION          274..315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          471..527
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        289..315
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        501..527
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   612 AA;  65437 MW;  DC67E3D42A295052 CRC64;
     MAHIGRTVKN VEAPRPLKSQ SRSSLKNNYM LIEELIQLIE NVALTLQSGI NNTEPMAALV
     QNLRIHGPQL ETVSKDTLDR AFVVFRNASQ DERLNIMTRL NLLELIELRA KGWEDNGFNS
     YYKTKQATNI DLPDGHVDPT QTGFLSTSPT FGGAGAAAAA AIAAVGSAQQ TQLLLAPGEV
     IRNSGKFLKP TKIPGKTYCK DEVVIRNADS GKVMGIKGRR VHMIEELSET IISFQRVNPG
     AKERLVQITG PTEEKINYAK QLIEDTIRRN ASPVRLDPAM GSGHAGGGGS CSSLASSNSD
     DVVTPRTPGG AGNSSLANRL SFNSAQNFMT ATAAATASQQ QQVMNMMGAV VGSTSTPTAA
     AAAAAAGEYK YTVNVGQHLI KITGDCCDLV RVAKLVLDDY FSSAEFLASV EAGAAFDGSI
     VSPIATPSTP MAAPQFMMGT PLHAAAPPLA DSGIGLNYMA VQGVNSNMHD GDDEVFADSN
     ATGQSNGLAR SRRSHFSRKD STPEAPTSST AARGKNESAT VGTVSSDSTR IVHEYEHLLY
     YSKSPHSWAL PVEWQKICEK FPAIVRNKDL ADENNRFDGE KYLELVKSAS KRNIAAATDE
     TTVGDTENQE NE
//