ID W8BYI7_CERCA Unreviewed; 1228 AA.
AC W8BYI7;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Retrovirus-related Pol polyprotein from transposon TNT 1-94 {ECO:0000313|EMBL:JAB98366.1};
DE Flags: Fragment;
GN Name=POLX {ECO:0000313|EMBL:JAB98366.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAB98366.1};
RN [1] {ECO:0000313|EMBL:JAB98366.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB98366.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
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DR EMBL; GAMC01008189; JAB98366.1; -; mRNA.
DR AlphaFoldDB; W8BYI7; -.
DR GO; GO:0042575; C:DNA polymerase complex; IEA:UniProt.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProt.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd09272; RNase_HI_RT_Ty1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR025724; GAG-pre-integrase_dom.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR013103; RVT_2.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR42648:SF18; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR Pfam; PF13976; gag_pre-integrs; 1.
DR Pfam; PF14223; Retrotran_gag_2; 1.
DR Pfam; PF00665; rve; 1.
DR Pfam; PF07727; RVT_2; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 2: Evidence at transcript level;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 155..170
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 372..550
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 658..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 671..687
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAB98366.1"
SQ SEQUENCE 1228 AA; 139316 MW; 38B1606F6FBBED9A CRC64;
SVKPSQLSYL KNCATAASAW KKLKEMHQPS GPVRKVSLYK QLLGLRMTDG DVMSSYLNKF
CSTVDKLSEV DIKISEELAV IILLSSLPKN YENFVIAVET RDNLPTLEVL KIKLLEEGER
RASESKMDYH SEQQAFQAKT KTIRKKRGDK NDVECYKCGQ RGHYKNQCRN KVREEPIKCQ
QQQHRSFTVL AATDVGELKY SSWCLDSGAT AHMSGARILF KNYIAQAEDV VLADNNVIRA
VGKGDVVLQT DLCKLTLENV LHVPQMKGNF ISVSRAVDRG CTVSFNNKYA IVSQEGEMIL
KAEKRNRLFV FESKNNTCFS AAQCSAEIWH NRYGHLNYGS LKSLVKNKMV LGIENMYISD
NTQCRTCMKS KIHTQPFPVA SESRAKKLLE LVHTDVCGPF EKRSLGGSSY FLTFIDDMSR
RIFTFFLKSK DEVFENFVTF KNMVERQTGQ KIKALRSDNG REYINKRFDD FLKQHGIARQ
LTIPYSPQQN GVAERANRTL VEMARSLLVH SNMPEFLWAE AVQSACYIRN RAPTSALVGM
TPYEAWSGRK PNVKNMRTFG SVAIGLDKTR KGKFHAKGKE YRFVGYSLVS KAYRLYDEER
HQIVEKRDVL FDEQVSVLEP DDQIAFDLPA DGATNDYRLE VGKLIPCKSE VEKEKVTCSE
DMQSDEYASA EEQEAEQKQD VKVGRGRPKY VRSGMPGRPK KKYNVIQAVQ SAEKQLPQTY
KEAISSEHVS YWQAAMEAEY DALVANSTWT VTDLPKGEQA IGCKWVYTVK RDKTGSVERY
KARLVAKGCA QRFGVNYTET FSPVCRYETI RLVLALSVQL KLYLHQMDVC TAYLNSELKD
VVYMKQPEGY ADRASSGKVL RLNKAIYGLK QAGREWNSML NGALCEIGFS QCQNEPCLYK
QDIKGSLCLI LIYVDDLLIA CQKKSDLMQV KSMISTKFEC VDKGPLQMFL GMQIQRDGEI
GDISMNQSLY ISDMLQRHDM QQCRTATTPL DTGYQIVCER ESCVKVDTKE YQSAIGELMW
LALTSRPDIY HSVVKLAQRN NNPHSEHFTG VKHVMRYLAA TRDLKLNYRA SGQALEGFVD
ADWGGDISNR RSYTGYIFFL AGGPISWKSE KQSSVALSST EAEYMALTSA AKEALHLRRL
IIEIGCGNAD TPTTLYGDNL SSQNLAKNPI YHARSKHIDI RHHFVREAIQ SGDVELKYIP
TEEMIADVLT KNLSKNKHLH FVKLMNLI
//
