ID   W8C1J2_CERCA            Unreviewed;       606 AA.
AC   W8C1J2;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Protein melted {ECO:0000313|EMBL:JAB95519.1};
DE   Flags: Fragment;
GN   Name=MELT {ECO:0000313|EMBL:JAB95519.1};
OS   Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC   Tephritidae; Ceratitis; Ceratitis.
OX   NCBI_TaxID=7213 {ECO:0000313|EMBL:JAB95519.1};
RN   [1] {ECO:0000313|EMBL:JAB95519.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Geib S.;
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:JAB95519.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA   Calla B., Hall B., Hou S., Geib S.M.;
RT   "A genomic perspective to assessing quality of mass-reared SIT flies used
RT   in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT   California.";
RL   BMC Genomics 15:98-98(2014).
CC   -!- SIMILARITY: Belongs to the MELT/VEPH family.
CC       {ECO:0000256|ARBA:ARBA00010187}.
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DR   EMBL; GAMC01011036; JAB95519.1; -; mRNA.
DR   AlphaFoldDB; W8C1J2; -.
DR   CDD; cd01264; PH_MELT_VEPH1; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR039888; Melted-like.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR21630:SF10; VENTRICULAR ZONE-EXPRESSED PH DOMAIN-CONTAINING PROTEIN HOMOLOG 1; 1.
DR   PANTHER; PTHR21630; VEPH-A/MELTED; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          484..579
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          1..136
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          163..184
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          250..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          585..606
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        46..61
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..117
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:JAB95519.1"
SQ   SEQUENCE   606 AA;  65999 MW;  B57A7D1D1BAE0CB9 CRC64;
     IHHSNNAGMT GVGGGGGGGP PTLVPPTPPH AGYTRRVKLG DSRSTGRLHP TGNTHRSMTR
     LNVAGGSVGG LHKSMTRLSS SQHINQNGGS SSNNANNSQS SGNVVVQTGT GASTTTVGAA
     AGAMPKTPTT PSSPGYVTPV PPLSNNVIIT GHNKWGIPST QVTSGGVTVT TSPTKVRPHS
     QGPTTLLNSS TALLKYSTDA INQSIGSISI PQNPVSVHHA SPALPQQNNG NQKSVMKLPV
     NGNSTHEVIV SGPTTNMTPR RNNNNTSRTL LNANNSCILD QRMSTFEPYQ IMRDPVQQFC
     EKHFGSIKSY MDEVSQSLPP PTRCSIEVSN EFAERRTKKV AKLHFACQIR GPHCMYSKTC
     FTMRTRNPKT WIHLMFLDFQ VRHYVKEKTV LSTREPGISN LKNIWQILKC ENRSFTELVT
     SQFPNSKDRE ILVNELRHSG FLDVFEVSKT DTSNPNCNEL EYQWGCLLCN HPDKAVGFLN
     GSNQPMIEGQ LKEKKGKWRL FRRWRTRYFT LSGAHLSCKG SSGGESIDVN QIRSVKVSRG
     ARNIPKAFEI FTADQTLILK PKDGKNAEEW VQCLSIVVAH SQARDNPTAK TNSLPARGMG
     SSKPSF
//