ID W8C5G9_CERCA Unreviewed; 752 AA.
AC W8C5G9;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=(Mediterranean fruit fly) hypothetical protein {ECO:0000313|EMBL:CAD6993734.1};
DE SubName: Full=Protein TRC8 {ECO:0000313|EMBL:JAB97514.1};
GN Name=TRC8 {ECO:0000313|EMBL:JAB97514.1};
GN ORFNames=CCAP1982_LOCUS2532 {ECO:0000313|EMBL:CAD6993734.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAB97514.1};
RN [1] {ECO:0000313|EMBL:JAB97514.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB97514.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
RN [3] {ECO:0000313|EMBL:CAD6993734.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EGII {ECO:0000313|EMBL:CAD6993734.1};
RA Whitehead M.;
RL Submitted (NOV-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CAJHJT010000001; CAD6993734.1; -; Genomic_DNA.
DR EMBL; GAMC01009041; JAB97514.1; -; mRNA.
DR EMBL; GAMC01009039; JAB97516.1; -; mRNA.
DR EMBL; GAMC01009035; JAB97520.1; -; mRNA.
DR RefSeq; XP_004530942.1; XM_004530885.2.
DR AlphaFoldDB; W8C5G9; -.
DR EnsemblMetazoa; XM_004530885.3; XP_004530942.1; LOC101460566.
DR GeneID; 101460566; -.
DR OrthoDB; 2912447at2759; -.
DR Proteomes; UP000606786; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16476; RING-H2_RNF139-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR025754; TRC8_N_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22763:SF163; E3 UBIQUITIN-PROTEIN LIGASE RNF139; 1.
DR PANTHER; PTHR22763; RING ZINC FINGER PROTEIN; 1.
DR Pfam; PF13705; TRC8_N; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Reference proteome {ECO:0000313|Proteomes:UP000606786};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT TRANSMEM 94..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..385
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..569
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 627..665
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 697..717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 733..752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 752 AA; 83772 MW; E893EC92AB966D78 CRC64;
MSVRTKVLGL VDVMMRVPPI LVIDEVLKIS MGLPTRFYPT PTDSNLLQTA EFTENHTQTH
TNMPTDASII FPELINSSLL NSTSSSDDSP LERAIVNAST TAATSGVLSS TFGVMMNELA
QDTFLSDVLS ITSVKFIICL IVFLSAACIF MLWTRYLVMV YMFVISLGLT FLSYWSNVSA
LTLMEKSPCI LEDLLSFNRT RLLDTGEVAM SLVPHLVAQW FMGMLFAYVH LGPRYRIVQK
IMPVVFASPI LLAMLPLPPR LIKDLPVFAG AVPLILTKAT MLNSAYDAAK TVYNGYQYAM
NFVSNFGLSA LIENEWQRLN VPSVLRVFWT IRIGQEFISI VLLSDSTTTI SFFPTMQKLL
VDGCETLTAV LGMTSIISVI CHYIGRAFQW YLLTFDNDEE KSLGTVSAVL FYILALQTGL
TSLAPDKRFV RLCRNLCLLI TALLHFLHNI VSPILMSLSA ARNPSRKRHI RALTVCAFLV
ATPICLLAAL WSRHTPSTWL LAVTAFSVEV VVKVLVSLAT YTLFLLDARR QTFWEKLDDY
LYYVRAFGNS VEFCFGILLF FNGAWILIFE SGGAIRAIMM CIHAYFNIWC EARAGWSVFM
KRRSAVHKIS ALPEATPAQL HAFDDVCAIC YQEMYSAKIT RCRHYFHGVC LRKWLYVQDR
CPLCHEIMMY TDKSDDSDAQ TPAESPAAAP IHLYNNEMDE DHNNSSTPRI ASNATTTSAA
ATTSSAAAVA TAAASNTTTQ SLRVSQDVGV QE
//
