ID W8C786_CERCA Unreviewed; 402 AA.
AC W8C786;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=(Mediterranean fruit fly) hypothetical protein {ECO:0000313|EMBL:CAD7003491.1};
DE SubName: Full=Tumor susceptibility gene 101 protein {ECO:0000313|EMBL:JAC05864.1};
GN Name=TS101 {ECO:0000313|EMBL:JAC05864.1};
GN ORFNames=CCAP1982_LOCUS11941 {ECO:0000313|EMBL:CAD7003491.1};
OS Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC Tephritidae; Ceratitis; Ceratitis.
OX NCBI_TaxID=7213 {ECO:0000313|EMBL:JAC05864.1};
RN [1] {ECO:0000313|EMBL:JAC05864.1}
RP NUCLEOTIDE SEQUENCE.
RA Geib S.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAC05864.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA Calla B., Hall B., Hou S., Geib S.M.;
RT "A genomic perspective to assessing quality of mass-reared SIT flies used
RT in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT California.";
RL BMC Genomics 15:98-98(2014).
RN [3] {ECO:0000313|EMBL:CAD7003491.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=EGII {ECO:0000313|EMBL:CAD7003491.1};
RA Whitehead M.;
RL Submitted (NOV-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. UEV
CC subfamily. {ECO:0000256|ARBA:ARBA00009594}.
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DR EMBL; CAJHJT010000034; CAD7003491.1; -; Genomic_DNA.
DR EMBL; GAMC01000692; JAC05864.1; -; mRNA.
DR RefSeq; XP_004520365.1; XM_004520308.2.
DR AlphaFoldDB; W8C786; -.
DR EnsemblMetazoa; XM_004520308.3; XP_004520365.1; LOC101458608.
DR GeneID; 101458608; -.
DR OrthoDB; 37962at2759; -.
DR Proteomes; UP000606786; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR Gene3D; 6.10.140.820; -; 1.
DR Gene3D; 6.10.250.370; -; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR037202; ESCRT_assembly_dom.
DR InterPro; IPR017916; SB_dom.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR InterPro; IPR008883; UEV_N.
DR PANTHER; PTHR23306:SF3; TUMOR SUPPRESSOR PROTEIN 101; 1.
DR PANTHER; PTHR23306; TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED; 1.
DR Pfam; PF05743; UEV; 1.
DR Pfam; PF09454; Vps23_core; 1.
DR SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS51312; SB; 1.
DR PROSITE; PS51322; UEV; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000606786};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 4..147
FT /note="UEV"
FT /evidence="ECO:0000259|PROSITE:PS51322"
FT DOMAIN 336..402
FT /note="SB"
FT /evidence="ECO:0000259|PROSITE:PS51312"
FT COILED 254..309
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 402 AA; 44957 MW; A12D8AA272D66465 CRC64;
MIPAADEAQI SKLLTKYKNI NATKKDVIDV VSTYRSLGYS LQKFVFNDGT TKELFNLAGT
IPVVYKNNTY YIPICIWLMD THPHNAPMCF VKPTPTMHIK VSMYVDHNGK IYLPYLHDWQ
PHTSDLLSLI QVMILTFGDH PPVFSKPRDP LSYSQAAGGG GYLPYPSANA GTSGSIPPYP
PVNSFGPYAS YSTGSNSTVA NASAVPGSYP PYMNFPQVPG YNSCYNSSTP SSTGTITEEH
IKASLISAVE DKLRRRLQEK VNQYQAEIET LNRTKQELVE GSLKIDNVIS RLNREEMELE
KNVSILRDKE QELVKCLEAF ENNKGIDPDE AVTTTAPIYR QLLNAYAEEA ALEDAIYYMG
EALRSNVIDL ETFLKHVRQL SRKQFMLRGI MQKCRQKAGL AG
//
