ID   W8C9F6_CERCA            Unreviewed;      1196 AA.
AC   W8C9F6;
DT   16-APR-2014, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 1.
DT   22-FEB-2023, entry version 18.
DE   SubName: Full=(Mediterranean fruit fly) hypothetical protein {ECO:0000313|EMBL:CAD7011646.1};
DE   SubName: Full=Rho GTPase-activating protein 19 {ECO:0000313|EMBL:JAC04362.1};
GN   Name=RHG19 {ECO:0000313|EMBL:JAC04362.1};
GN   ORFNames=CCAP1982_LOCUS19733 {ECO:0000313|EMBL:CAD7011646.1};
OS   Ceratitis capitata (Mediterranean fruit fly) (Tephritis capitata).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Tephritoidea;
OC   Tephritidae; Ceratitis; Ceratitis.
OX   NCBI_TaxID=7213 {ECO:0000313|EMBL:JAC04362.1};
RN   [1] {ECO:0000313|EMBL:JAC04362.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Geib S.;
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:JAC04362.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=24495485; DOI=10.1186/1471-2164-15-98;
RA   Calla B., Hall B., Hou S., Geib S.M.;
RT   "A genomic perspective to assessing quality of mass-reared SIT flies used
RT   in Mediterranean fruit fly (Ceratitis capitata) eradication in
RT   California.";
RL   BMC Genomics 15:98-98(2014).
RN   [3] {ECO:0000313|EMBL:CAD7011646.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=EGII {ECO:0000313|EMBL:CAD7011646.1};
RA   Whitehead M.;
RL   Submitted (NOV-2020) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CAJHJT010000056; CAD7011646.1; -; Genomic_DNA.
DR   EMBL; GAMC01002194; JAC04362.1; -; mRNA.
DR   AlphaFoldDB; W8C9F6; -.
DR   Proteomes; UP000606786; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR14963; RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED; 1.
DR   PANTHER; PTHR14963:SF7; RHO GTPASE-ACTIVATING PROTEIN 19; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome {ECO:0000313|Proteomes:UP000606786}.
FT   DOMAIN          92..306
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          434..461
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          488..557
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          570..597
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          757..783
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          798..823
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1027..1047
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1075..1109
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        570..590
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1084..1109
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1196 AA;  132125 MW;  F85AC2D0DFD54015 CRC64;
     MDLDYVNLNR LSDREIAAHM RKLNYEKFKS LVRMHLSFEL DLNTDEFDLP CHEIVYEDKG
     KLKKWNRLSK KQKHASTSCT NASKGSISAE NSPVELLNQQ INAGFLMHLE ELKQFLLLEK
     NLTQEGIFRK TGSASRQNEL RQQVQNDKPL DLEGGGYSAH DCATVFKGYL ADLPEPLLTD
     AHYPAHQQIA PLCLGSGSNS SSSTGTLTRP HNPERIKREQ HLLNSIQLLL LLLPDENRQL
     LQHIIEILHA VSTFQNQNKM TPENLATIFA PHLICPRNLP PEALHYISKT MSSIIAYMVC
     KGQEIFEMPA KLSTDIRAYF MERKRKKTMS PEQTLDESIS DMSTVNTVYT FVDREKTAAA
     HTANNTDTEL AQLYAHIQSL PESSKKRRLI KQFNKQNGQG TPLQLVVMNR LKGTDASRSA
     KSIGDSIKKH IFHKGLISRT PKRPAAATTT PPAGVETPIF ANTHKNPKLR VLFRSPALSQ
     ISNSYSVANT PIRSSSSSTS TSTTTQSLHV TNRTHINTPS SSCASSTSSL STTPFSTKSL
     HQHPLHKSIS SNSLLSHSSA TEQHKLTLQQ NVNDEVSESS SLSSTSSDGM PLAPAPKYDC
     SVSAPVSRQN SEESNTGASF TNRFALRWDA SCCTPLKLSS DTTKQQTAAG NATDARKTVA
     WDEAHLLDIE EISNPCTPIQ QNSAGYKSRY KSEPNLSCAS ETVAMRANTQ ESTSKYASGS
     RSLTRKLMKG VSMSNLKFSF ATPESTKRLV RSVSSTLMRR SAGEDELSKS GCVSTKGKEE
     TAEATNAVVA EGLEDLDDET FEDNPDDHLD SDSDADVLDE EEEVEAYDSV YATAYNVGVT
     AVDGRSSNSN SSDSSISRYH QHLLLQQSGV YRNMELITST PSMLLGRRSM SPITKSTQRM
     PKAMQESIMT PRSRKPVMVL TTTTHSTSDQ NQTICQTDFA SFREQDEDES KHSRASADYI
     QRSEVDAAPH LQCEDATSLE SYTELMRARL PALAALKHNE PSVVKVDALS NNFKEYLRSR
     SVLTASPVDT SFSSQPDDFG TPEKNIEDLN DSQLSPSLLY CLDGNEPDLN AIVDEKSKKP
     PSEEPILKST SASENSVEMS AATSSGSQCC TPHNSYYRNR LYALNNVRKR AANSEYEKNE
     IKTPLITTAA ATGIGVTSDN QNSMPTTANK ENIEQVEGYL RSRKLLISEY PGETSF
//