ID W8QMR6_9BACT Unreviewed; 110 AA.
AC W8QMR6;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=isocitrate lyase {ECO:0000256|ARBA:ARBA00012909};
DE EC=4.1.3.1 {ECO:0000256|ARBA:ARBA00012909};
DE AltName: Full=Isocitrase {ECO:0000256|ARBA:ARBA00031022};
DE AltName: Full=Isocitratase {ECO:0000256|ARBA:ARBA00031921};
DE Flags: Fragment;
GN Name=aceA {ECO:0000313|EMBL:AHL38433.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:AHL38433.1};
RN [1] {ECO:0000313|EMBL:AHL38433.1}
RP NUCLEOTIDE SEQUENCE.
RA Beier S., Galvez M.J., Molina V., Blain S., Obernosterer I.;
RT "The transcriptional regulation of the glyoxylate cycle in response to iron
RT depletion in the Southern Ocean.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-threo-isocitrate = glyoxylate + succinate;
CC Xref=Rhea:RHEA:13245, ChEBI:CHEBI:15562, ChEBI:CHEBI:30031,
CC ChEBI:CHEBI:36655; EC=4.1.3.1;
CC Evidence={ECO:0000256|ARBA:ARBA00023531};
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DR EMBL; KF991409; AHL38433.1; -; Genomic_DNA.
DR AlphaFoldDB; W8QMR6; -.
DR GO; GO:0004451; F:isocitrate lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR InterPro; IPR006254; Isocitrate_lyase.
DR InterPro; IPR018523; Isocitrate_lyase_ph_CS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR PANTHER; PTHR21631:SF3; BIFUNCTIONAL GLYOXYLATE CYCLE PROTEIN; 1.
DR PANTHER; PTHR21631; ISOCITRATE LYASE/MALATE SYNTHASE; 1.
DR Pfam; PF00463; ICL; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR PROSITE; PS00161; ISOCITRATE_LYASE; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:AHL38433.1}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AHL38433.1"
FT NON_TER 110
FT /evidence="ECO:0000313|EMBL:AHL38433.1"
SQ SEQUENCE 110 AA; 11918 MW; BC308221CCD6B307 CRC64;
PLNVFELTKK FIKAGAAGVH FEDQLASEKK CGHMGGKVLV PTGTMIKNLK AARLAADIAE
VPLIILARTD ANAAKLITND FDENDKPFLT GERSPEGFYY VKQGIEQAIS
//
