ID W8QNY0_9HIV1 Unreviewed; 156 AA.
AC W8QNY0;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Env polyprotein {ECO:0000256|ARBA:ARBA00029888};
DE Flags: Fragment;
GN Name=env {ECO:0000313|EMBL:AHL46241.1};
OS Human immunodeficiency virus 1.
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX NCBI_TaxID=11676 {ECO:0000313|EMBL:AHL46241.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1] {ECO:0000313|EMBL:AHL46241.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=H058760 {ECO:0000313|EMBL:AHL46241.1};
RX PubMed=24595023;
RA Grabowski M.K., Lessler J., Redd A.D., Kagaayi J., Laeyendecker O.,
RA Ndyanabo A., Nelson M.I., Cummings D.A., Bwanika J.B., Mueller A.C.,
RA Reynolds S.J., Munshaw S., Ray S.C., Lutalo T., Manucci J., Tobian A.A.,
RA Chang L.W., Beyrer C., Jennings J.M., Nalugoda F., Serwadda D., Wawer M.J.,
RA Quinn T.C., Gray R.H.;
RT "The Role of Viral Introductions in Sustaining Community-Based HIV
RT Epidemics in Rural Uganda: Evidence from Spatial Clustering, Phylogenetics,
RT and Egocentric Transmission Models.";
RL PLoS Med. 11:E1001610-E1001610(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cell
CC membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004251}. Host cell membrane
CC {ECO:0000256|ARBA:ARBA00004505}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004505}. Host cell membrane
CC {ECO:0000256|ARBA:ARBA00004402}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004402}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}. Virion membrane
CC {ECO:0000256|ARBA:ARBA00004650}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004650}. Virion membrane
CC {ECO:0000256|ARBA:ARBA00004563}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004563}.
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DR EMBL; KJ374489; AHL46241.1; -; Genomic_DNA.
DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
DR GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR CDD; cd09909; HIV-1-like_HR1-HR2; 1.
DR Gene3D; 1.10.287.210; -; 1.
DR Gene3D; 1.20.5.490; Single helix bin; 1.
DR InterPro; IPR000328; GP41-like.
DR Pfam; PF00517; GP41; 1.
DR SUPFAM; SSF58069; Virus ectodomain; 1.
PE 4: Predicted;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Host cell membrane {ECO:0000256|ARBA:ARBA00022511};
KW Host membrane {ECO:0000256|ARBA:ARBA00022870};
KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022581};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Viral envelope protein {ECO:0000313|EMBL:AHL46241.1};
KW Virion {ECO:0000313|EMBL:AHL46241.1}.
FT DOMAIN 3..155
FT /note="Retroviral envelope protein GP41-like"
FT /evidence="ECO:0000259|Pfam:PF00517"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AHL46241.1"
FT NON_TER 156
FT /evidence="ECO:0000313|EMBL:AHL46241.1"
SQ SEQUENCE 156 AA; 18407 MW; AD64B9FD2EC97466 CRC64;
STMGAASLTL TVQARQLLSG IVQQQNNLLR AIEAQQHLLQ LTVWGIKQLQ ARILAVERYL
KDQQLLGVWG CSGKHICTTN VPWNSSWSNR SLEEIWGNMT WMEWEREIDN YTDLIYTLIE
ESQIQQDKNE KDLLQLDKWA SLWNWFTITN WLWYIX
//
