ID W8S6H8_9RHOB Unreviewed; 629 AA.
AC W8S6H8;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Acetyl-coenzyme A synthetase {ECO:0000313|EMBL:AHM05882.1};
DE EC=6.2.1.1 {ECO:0000313|EMBL:AHM05882.1};
GN ORFNames=roselon_03638 {ECO:0000313|EMBL:AHM05882.1};
OS Roseibacterium elongatum DSM 19469.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseibacterium.
OX NCBI_TaxID=1294273 {ECO:0000313|EMBL:AHM05882.1, ECO:0000313|Proteomes:UP000019593};
RN [1] {ECO:0000313|EMBL:AHM05882.1, ECO:0000313|Proteomes:UP000019593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19469 {ECO:0000313|Proteomes:UP000019593};
RA Fiebig A., Goeker M., Klenk H.-P.P.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CP004372; AHM05882.1; -; Genomic_DNA.
DR RefSeq; WP_025313481.1; NZ_CP004372.1.
DR AlphaFoldDB; W8S6H8; -.
DR STRING; 1294273.roselon_03638; -.
DR KEGG; red:roselon_03638; -.
DR PATRIC; fig|1294273.3.peg.3592; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_3_5_5; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000019593; Chromosome.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR CDD; cd05967; PrpE; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Ligase {ECO:0000313|EMBL:AHM05882.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019593}.
FT DOMAIN 3..57
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 64..444
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 510..588
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 629 AA; 68420 MW; 95D3EAC7074C0295 CRC64;
MTYGDLYESA KRDPDAFWME AAKGIDWDVQ PSKALFDENA PLYEWYADGK LNACWNAVDR
HVEAGHGDRT AIIYDSPVTH TKREITFVEL RNRVATLAGA LRAKGVGKGD RVIIYMPMIP
EALEAMLACA RLGAVHSVVF GGFASHELAV RIDDCTPKCI IAASCGIEPG RVVHYKPLLD
GALDQATHQP DFCVIYQREQ EVAHLEEGRD VNWHGFQYGV EPADCVPVEG NHPLYILYTS
GTTGQPKGVV RHTGGHSVAL NWTMKNLYDM NPGEVFWAAS DVGWVVGHSY ICYGPLTYGC
TTVVFEGKPV GTPDAGTFWR VIRDHKVKCL FTAPTAFRAI KRDDPTGSLV GDYDLSSLKS
LFLAGERADP DTIEWAQDKL GVPVIDHWWQ TETGWAIAGN PLGVEALPVK IGSPSVAMPG
YDVQILDEGG HPMKTGELGA IAVKLPLPPG TLPTLWQAED RFHASYLTHF PGYYETGDAG
MIDEDGYLYI MARTDDVINV AGHRLSTGAM EEVLAAHADV AECAVIGVAD ALKGQLPMGF
LCLNKGAETA PEQVVKDCVK MVRDQIGPVA AFKLAVVVDR LPKTRSGKIL RGTMVKIADG
QEFKMPATID DPAILDEIAE AVKPLGYGA
//
