ID W8V0U5_KLEPN Unreviewed; 406 AA.
AC W8V0U5;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Alanine racemase family protein {ECO:0000313|EMBL:AHM81543.1};
GN ORFNames=KPNJ2_04767 {ECO:0000313|EMBL:AHM81543.1};
OS Klebsiella pneumoniae 30684/NJST258_2.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=1420013 {ECO:0000313|EMBL:AHM81543.1, ECO:0000313|Proteomes:UP000019586};
RN [1] {ECO:0000313|EMBL:AHM81543.1, ECO:0000313|Proteomes:UP000019586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=30684/NJST258_2 {ECO:0000313|EMBL:AHM81543.1};
RX PubMed=24639510; DOI=10.1073/pnas.1321364111;
RA Deleo F.R., Chen L., Porcella S.F., Martens C.A., Kobayashi S.D.,
RA Porter A.R., Chavda K.D., Jacobs M.R., Mathema B., Olsen R.J., Bonomo R.A.,
RA Musser J.M., Kreiswirth B.N.;
RT "Molecular dissection of the evolution of carbapenem-resistant multilocus
RT sequence type 258 Klebsiella pneumoniae.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:4988-4993(2014).
CC -!- SIMILARITY: Belongs to the DSD1 family.
CC {ECO:0000256|ARBA:ARBA00005323}.
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DR EMBL; CP006918; AHM81543.1; -; Genomic_DNA.
DR RefSeq; WP_002887552.1; NZ_CP006918.1.
DR AlphaFoldDB; W8V0U5; -.
DR KEGG; kps:KPNJ2_04767; -.
DR PATRIC; fig|1420013.3.peg.4478; -.
DR HOGENOM; CLU_031639_3_0_6; -.
DR Proteomes; UP000019586; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProt.
DR CDD; cd06818; PLPDE_III_cryptic_DSD; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR Gene3D; 2.40.37.20; D-serine dehydratase-like domain; 1.
DR InterPro; IPR001608; Ala_racemase_N.
DR InterPro; IPR026956; D-ser_dehydrat-like_dom.
DR InterPro; IPR042208; D-ser_dehydrat-like_sf.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR28004:SF8; D-SERINE DEAMINASE; 1.
DR PANTHER; PTHR28004; ZGC:162816-RELATED; 1.
DR Pfam; PF01168; Ala_racemase_N; 1.
DR Pfam; PF14031; D-ser_dehydrat; 1.
DR SMART; SM01119; D-ser_dehydrat; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
PE 3: Inferred from homology;
FT DOMAIN 295..393
FT /note="D-serine dehydratase-like"
FT /evidence="ECO:0000259|SMART:SM01119"
SQ SEQUENCE 406 AA; 44136 MW; CBD82F079C87F1AE CRC64;
MKYHSAPLIP HKSALMSAPA NLLAEEVCLP AALLKKSALE NNISWMQRYA DARGVSLAPH
GKTTMTPWIF QAQQRAGAWG IGVGSAWQAS AAMASGIQRV LMVNQLVGKA NMQVVAQLKA
HYRAVDFICC VDSEVNVRAL STFFADQGQT LDVLIELGVP GGRCGCRSVN DALALAQRVS
DLPGLRLRGL ELYEGVLHGD DPQPQVEALL QQAAALACRM EPLVDGEFIL TGAGTVWYDV
VCNIWLAAAK PRRCRIVIRP GCYITHDRGI YDLAQQELIA RDPIACDLAG DLTSALELMA
MVQSVPEADR AVVNFGKRDC AFDAGLPQPI AHYRNGQELA LRAESIVSTG IMDQHCMLRL
APGSDVQVGD ILLFGTSHPC LTFDKWKTLL LVDDDYNVLD ELDTLF
//
