ID   W9EM06_9LACO            Unreviewed;       798 AA.
AC   W9EM06;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   RecName: Full=Probable phosphoketolase {ECO:0000256|HAMAP-Rule:MF_01403};
DE            EC=4.1.2.- {ECO:0000256|HAMAP-Rule:MF_01403};
GN   ORFNames=B808_376 {ECO:0000313|EMBL:ETO40714.1};
OS   Fructilactobacillus florum 8D.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Fructilactobacillus.
OX   NCBI_TaxID=1221538 {ECO:0000313|EMBL:ETO40714.1, ECO:0000313|Proteomes:UP000019474};
RN   [1] {ECO:0000313|EMBL:ETO40714.1, ECO:0000313|Proteomes:UP000019474}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=8D {ECO:0000313|EMBL:ETO40714.1,
RC   ECO:0000313|Proteomes:UP000019474};
RA   Kim E.B., Marco M.L.;
RT   "Genome sequencing of Lactobacillus florum 8D.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964,
CC         ECO:0000256|HAMAP-Rule:MF_01403};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000256|ARBA:ARBA00005623,
CC       ECO:0000256|HAMAP-Rule:MF_01403}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETO40714.1}.
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DR   EMBL; ALXG01000015; ETO40714.1; -; Genomic_DNA.
DR   RefSeq; WP_009166338.1; NZ_ALXG01000015.1.
DR   AlphaFoldDB; W9EM06; -.
DR   PATRIC; fig|1221538.3.peg.382; -.
DR   OrthoDB; 9768449at2; -.
DR   Proteomes; UP000019474; Unassembled WGS sequence.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   PANTHER; PTHR31273; PHOSPHOKETOLASE-RELATED; 1.
DR   PANTHER; PTHR31273:SF0; PHOSPHOKETOLASE-RELATED; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_01403};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019474};
KW   Thiamine pyrophosphate {ECO:0000256|HAMAP-Rule:MF_01403}.
FT   DOMAIN          7..376
FT                   /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT                   phosphoketolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09364"
FT   DOMAIN          593..793
FT                   /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT                   phosphoketolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09363"
FT   REGION          358..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   798 AA;  90436 MW;  4184189A492B2547 CRC64;
     MSVDYDSKAY FDKMTQYWNT ANYLSVGQLF LRSNPMLKEP LTAADVKVKP IGHWGTIASQ
     NFIYTHLNRV INKYDLNMFY IEGSGHGGQV MVSNSYIDGS YSDIYPEITA DEAGMSKLFK
     QFSFPGGIAS HAAPETPGSI HEGGELGYSL SHGVGAIFDN PEVIAAVEIG DGEAETGPLA
     GSWFSSSFIN PVTDGAVLPI INLNGFKIAN PTIFNRTSDE DLQKYFEGLG WKPYFVETNL
     PHGENIDETN VNLAKAMDAA VEDIQAIQKK ARETETAETA KRPVWPMIIF RSPKGWTGPQ
     ENAKGLPIEG SFRAHQVPLP LSADNMETAD EFVKWMESYK PADSFNEDGT IKEEIKSLAP
     KGDRRMSVNP ITNGGLDPKP LDLPDFRDYA VEIKTPGATD AEDMVVWSEW VRDTMKKNPT
     TFRAFGPDET WSNRIWHIFD TTNRQWSRDI DTPYDEYMAH EGRVIDSQLS EHDDEGWLEG
     YVLTGRHGFF ATYESFGRVV DSMLTQHFKW LRKASEMGWR KQYPSLNFID SSTVFQQDHN
     GYTHQDPGMI NHLAEKKPEF IREYFPADAN TLLATANVAF ADYEKINLIT TSKHPRPQWF
     NIDEADQLVN KGLGYIDWAS TDQGTEPDIV MASAGVEPTM ETLAAINLLH DRFPELKIRY
     INVVDLLKLR SPKQDPRGLS DKEFNDLFTT DKPVVFAFHG FEDIIRTIFF DRDNKNVHIH
     GYRENGDITT PFDMRVLNQL DRFDLAKEVV QAVPGMAEQN ADFVQEMEDW VAKHNHYIRT
     EGTDLPEVTN WKWKPLNK
//