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Database: UniProt
Entry: W9GB13_9MICO
LinkDB: W9GB13_9MICO
Original site: W9GB13_9MICO 
ID   W9GB13_9MICO            Unreviewed;       543 AA.
AC   W9GB13;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   05-JUL-2017, entry version 27.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=N865_12020 {ECO:0000313|EMBL:EWT01034.1};
OS   Intrasporangium oryzae NRRL B-24470.
OC   Bacteria; Actinobacteria; Micrococcales; Intrasporangiaceae;
OC   Intrasporangium.
OX   NCBI_TaxID=1386089 {ECO:0000313|EMBL:EWT01034.1, ECO:0000313|Proteomes:UP000019489};
RN   [1] {ECO:0000313|EMBL:EWT01034.1, ECO:0000313|Proteomes:UP000019489}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-24470 {ECO:0000313|EMBL:EWT01034.1,
RC   ECO:0000313|Proteomes:UP000019489};
RA   Liu H., Wang G.;
RT   "Intrasporangium oryzae NRRL B-24470.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EWT01034.1}.
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DR   EMBL; AWSA01000029; EWT01034.1; -; Genomic_DNA.
DR   EnsemblBacteria; EWT01034; EWT01034; N865_12020.
DR   PATRIC; fig|1386089.3.peg.2739; -.
DR   Proteomes; UP000019489; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000019489};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019489}.
FT   DOMAIN      236    370       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      448    517       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     244    251       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   543 AA;  60102 MW;  F92D4C9464B4C304 CRC64;
     MTDGDVDYGR IWQQTLGTLD SVGLSSQERA FVRLCRLVGV LDQTALVKAP NAFTKDFLET
     RVREQVVRAL TDHLRHPVQL AVSVDESLET DLGLITDEPA GQPALSDRSR LGMSVSPLGM
     PMPGSIGSVG SVGSGIPLAP PEPIQTRLTV QGGFVRNPLK DLEESAPALN GADLDDPGHP
     LSGGESGPLR QQRIEPPSTG DTRLNPKYTF DTFVIGASNR FAHAAAVAVA EAPAKAYNPL
     FVYGESGLGK THLLHAIGHY ARTMFPNVRV RYVNSEEFTN DFINSIRDDK ASAFQSRYRN
     VDVLLIDDIQ FLQGKLQTQE EFFHTFNTLH NANKQIVITS DLPPKELSGF EDRMRTRFES
     GLLTDVQPPD LETRIAILRK KAIQDRMSVP DDVLEYIATN FSTNIRELEG ALIRVTAFSN
     LNRQAVDLPL AEIVLKDVLP NETPNQVTAA TIMAVTAAYY AVTMEDLCGS SRSRQLVTAR
     QIAMYLCREM TDLSLPKIGQ HFGGRDHTTV MHADRKIREL MGERRAIYNQ VTELTNRIRQ
     QSH
//
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