ID W9GGF4_9MICO Unreviewed; 407 AA.
AC W9GGF4;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:EWT05316.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:EWT05316.1};
GN ORFNames=N864_24255 {ECO:0000313|EMBL:EWT05316.1};
OS Intrasporangium chromatireducens Q5-1.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Intrasporangium.
OX NCBI_TaxID=584657 {ECO:0000313|EMBL:EWT05316.1, ECO:0000313|Proteomes:UP000019494};
RN [1] {ECO:0000313|Proteomes:UP000019494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Q5-1 {ECO:0000313|Proteomes:UP000019494};
RA Liu H., Wang G.;
RT "Intrasporangium oryzae NRRL B-24470.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWT05316.1}.
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DR EMBL; AWQS01000124; EWT05316.1; -; Genomic_DNA.
DR RefSeq; WP_034717905.1; NZ_AWQS01000124.1.
DR AlphaFoldDB; W9GGF4; -.
DR PATRIC; fig|584657.3.peg.2805; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000019494; Unassembled WGS sequence.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF8; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:EWT05316.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019494};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:EWT05316.1}.
FT DOMAIN 5..275
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 283..405
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 90
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 362
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 392
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 407 AA; 42589 MW; 4EDA6B18CE4C9DCD CRC64;
MPEAVIVSTA RSPFGRAFKG SLKQVRPDDL AATVIQAALD KVPALDKNLI EDIYLGCAEP
SGRHGSNMAK VVSTLLGIDN TPGATVNRFC ASSAQTTRMA FHAIKAGEGD IFVSAGVECV
SQYTDWAGAG GAATDVQNPR FADAQERTAK LAQTNETWTD PRENGALPDI YVAMGQTAEN
VATAYGISRE RQDEWGVTSQ NRAEAAIGRG FFDWEITPIT TPDGTVVSKD DGPRAGVTLE
AVQSLNPVFR ENGTVTAGNC CPLNDGAAAL VVMSDTKAKE LGLTPLARVV STAATGLSPE
IMGLGPIEAS KLALQRAGMT IGDMDLYEIN EAFAAQVIGS ADALGMDYDK LNVNGGAIAI
GHPFGATGAR ITGTIINALR DRDQQFGLET MCVGGGQGMA VIFERLS
//
