ID W9ISR9_FUSOX Unreviewed; 243 AA.
AC W9ISR9;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Endosomal/vacuolar adapter protein YPT35 {ECO:0000256|ARBA:ARBA00033774};
DE AltName: Full=PX domain-containing protein YPT35 {ECO:0000256|ARBA:ARBA00033785};
GN ORFNames=FOYG_04581 {ECO:0000313|EMBL:EWY95571.1};
OS Fusarium oxysporum NRRL 32931.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=660029 {ECO:0000313|EMBL:EWY95571.1, ECO:0000313|Proteomes:UP000030753};
RN [1] {ECO:0000313|EMBL:EWY95571.1, ECO:0000313|Proteomes:UP000030753}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FOSC 3-a {ECO:0000313|Proteomes:UP000030753};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum FOSC 3-a.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Recruits the lipid transfer protein VPS13 to endosomal and
CC vacuolar membranes. {ECO:0000256|ARBA:ARBA00033728}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000256|ARBA:ARBA00004148};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004148}.
CC -!- SIMILARITY: Belongs to the YPT35 family.
CC {ECO:0000256|ARBA:ARBA00007426}.
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DR EMBL; JH717841; EWY95571.1; -; Genomic_DNA.
DR AlphaFoldDB; W9ISR9; -.
DR HOGENOM; CLU_070610_1_2_1; -.
DR OrthoDB; 2041724at2759; -.
DR Proteomes; UP000030753; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:InterPro.
DR CDD; cd07280; PX_YPT35; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR037917; Ypt35_PX.
DR PANTHER; PTHR45949; SORTING NEXIN-4; 1.
DR PANTHER; PTHR45949:SF2; SORTING NEXIN-4; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000030753};
KW Vacuole {ECO:0000256|ARBA:ARBA00022554}.
FT DOMAIN 117..243
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..72
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 243 AA; 26857 MW; 13D473D632CC00B6 CRC64;
MATAIDQAPG DGNLAAGASH PGSSETQTAA TEVFETPRTS FDHDPNNSNH ARHEPASSTV
SPSSITSPPY WLNTRAGHQR TISNMSTESV LPAGAITLRD NEASEFDDRN SACWAKSVEV
VSYTIVNGSA TNIGAFVVWN IRVEALNGSY MNIRKRYSEF DDFRYRLVQT FPGFEAAVPA
LPPKSVISKF RPRFLEKRRA GLQYFLKCVY QEFPAQYYAD LISCILLNPE FSGSPVLKEF
LFA
//
