ID W9K1Z7_FUSOX Unreviewed; 1658 AA.
AC W9K1Z7;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};
GN ORFNames=FOZG_11394 {ECO:0000313|EMBL:EWZ35478.1};
OS Fusarium oxysporum Fo47.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=660027 {ECO:0000313|EMBL:EWZ35478.1};
RN [1] {ECO:0000313|EMBL:EWZ35478.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Fo47 {ECO:0000313|EMBL:EWZ35478.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum Fo47.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EWZ35478.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Fo47 {ECO:0000313|EMBL:EWZ35478.1};
RG The Broad Institute Genomics Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "Annotation of the Genome Sequence of Fusarium oxysporum Fo47.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU004279}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU004279};
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|RuleBase:RU004279}.
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DR EMBL; JH717903; EWZ35478.1; -; Genomic_DNA.
DR VEuPathDB; FungiDB:FOZG_11394; -.
DR HOGENOM; CLU_000487_2_4_1; -.
DR Proteomes; UP000030766; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd02735; RNAP_I_Rpa1_C; 1.
DR CDD; cd01435; RNAP_I_RPA1_N; 1.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 1.10.357.120; -; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.30.70.2850; -; 2.
DR Gene3D; 3.30.1490.180; RNA polymerase ii; 1.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR047107; DNA-dir_RNA_pol1_lsu_C.
DR InterPro; IPR015699; DNA-dir_RNA_pol1_lsu_N.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR000722; RNA_pol_asu.
DR InterPro; IPR006592; RNA_pol_N.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF11; DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 2.
DR Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SMART; SM00663; RPOLA_N; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU004279};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU004279}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004279};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004279}.
FT DOMAIN 363..683
FT /note="RNA polymerase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00663"
FT REGION 268..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1350..1431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 407..434
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1386..1416
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1658 AA; 182756 MW; C636E558AC1258FC CRC64;
MNIAQPVASG VESVEFTFLS PKEIRAISVK RIENPETFDN LLNPVPGGLY DPALGSWGDA
PCTTCNLNQA TCPGHAGHIQ LPVPVYHPVF MDQAYRLLKA ACVYCKGFRL PQKELHKYVC
QLKLLQHGLI QEAHVVGAIG DNELAIELGD FSELESEAEE EGGTNSIDNV TRARDKYVDK
CLSGIKIKRG DTKRGKHEGS SEMRREIIKE FLAEITKRRV CASCGGISPS YRKDRFVKVF
ERSLSDKDKA KMAQKNFKQA DAMARVHQAA TKQKPDGYSS DEGVADVASP TRETSRVNGD
VTDQDTEMID ADTASTSSSP QRYISAMEVR ARLNELFTKE QELVSLLYNA KPPTRSSTNV
TPDMFFLTTI LVPPNRYRPE ARTGESEISE AQQNSLYKNI LRGCGTIARL HRELQEEKAD
VNRMHQASAE LQESVNALID KNKNPVQGAA AKRNEDGIKQ KLEKKEGLFR KNMMGKRVNY
AARSVISPDP NIETNEIGVP PVFAKKLTYP EPVTSHNFRD MQQAVINGVD KWPGAFAIEN
ENGQIVNLRN KSVDDRVSLA NQLLAPTSSN AARTRNKKVY RHLTNGDVVL MNRQPTLHKP
SIMGHRVRVL PGEKTIRMHY ANCNTYNADF DGDEMNMHFP QNEVARAEAL QIADTDHQYL
SGTAGKPLRG LIQDHISVSV ALCNRDTFFT KGDYQQLVYN ALRPESGHIV GERIELVAPA
VIRPVARWTG KQVITTILKN MQPPNCGGLS MKAETQIKAS QWGVNSEEGT VVFQDGEFIA
GILDKSQIGP SSGGVIHAVH EIYGPAVAGK LLSSLGRLLT RYLNMRAFSC GMDDLRLTPE
GEQARREALV PADSVGLKVA SSYVSLEQDP GPRDPLLLER LEEVLRDDSK QEGLDLLMKE
GLSKITDKIQ TATMPVGLEK AFPFNQMQAM TTSGAKGSRV NASLISCNLG QQVLEGRRVP
IMVSGKSLPC FNPFETHARA GGYIVQRFLT GIRPQEYYFH HMAGREGLID TAVKTSRSGY
LQRCVIKGME GLTVAYDTTV RDADGSMIQF LYGEDGLDVS KQKYLTDFSF ILENVTSEAS
QLRYDPSVGD RLGMHRDAIT KYMKKALKHT NIKDPKAQDP ISGLFNPATT AFATSENFYK
AMTSYIKENK DGLVRDKSDK NKLALSRVSL NKKNAEMLFA MKYLRSLVEP GEAVGIVAGQ
SVGEPSTQMT LNTFHLAGHS AKNVTLGIPR LREILMTASD KISTPAMSIY PIEEMSVEDA
EIFAKSISVL PLGFILDSIN VEEKFFDSEE YTKTYAINIS DVVEAVERKL LHRLLALVKK
DIRKRMTMST MATPDVGAKA GVVETAAPNA EAAGNFDDDE DDEDGDDDAT NAKQRAKRSE
AVSYGPNDDD DDAVQQEMER DAGDDDADED EDFGGSPQQA EGDGDGDDVD WSAKARTNRV
LEQYAEVTDF SFDEKTGASC SFTLEYDSTI PKVLMLNLVQ DAVRKTVIQE ISGVGACTLV
EEKDTKVIHT AGVNLQAMQR YSDFIDPNRI QTNDIAAVLA VYGVEAARQN IVQELAGVFG
SHGIKVDNRH LNLIGDHMTR NGGFTPFNRM GLKGNVSPFT KMSFETTLAF LKDAVLDGDW
DDLSTPSGRL VMGRLGKVGT GGFDVLAQLP TYHVDSLA
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