ID W9P5S5_FUSOX Unreviewed; 1710 AA.
AC W9P5S5;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Rho1 guanine nucleotide exchange factor 3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=FOVG_09267 {ECO:0000313|EMBL:EXA40428.1};
OS Fusarium oxysporum f. sp. pisi HDV247.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1080344 {ECO:0000313|EMBL:EXA40428.1};
RN [1] {ECO:0000313|EMBL:EXA40428.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HDV247 {ECO:0000313|EMBL:EXA40428.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum HDV247.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EXA40428.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HDV247 {ECO:0000313|EMBL:EXA40428.1};
RG The Broad Institute Genomics Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "Annotation of the Genome Sequence of Fusarium oxysporum HDV247.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH650973; EXA40428.1; -; Genomic_DNA.
DR HOGENOM; CLU_001083_2_0_1; -.
DR Proteomes; UP000030751; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041675; PH_5.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46572:SF1; RHO1 GUANINE NUCLEOTIDE EXCHANGE FACTOR TUS1; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF15405; PH_5; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00036; CNH; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50219; CNH; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
FT DOMAIN 887..1079
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 1344..1653
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 1..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..641
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1193..1233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1652..1681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..575
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..630
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1194..1233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1655..1679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1710 AA; 189703 MW; A46A4D98B001E98A CRC64;
MSFRGDDQRR YGHVPPVQYP VAGRGQEYQQ QQQQQQQPHS SYDDIGRRAS FNGGDDAAYI
QPPINRSPAF GGSGEDELFM NNNAAARPGY GSTNNALSGY QHQYQDVPPT PTYSYNPQSF
AQTSGFSRST STNALPYRNQ HQPQPPSRYA SNASSYTPQA YDPSAYASTN VPQRQASYQG
YNTYGQSYGS QTSPGFNQST GSYPQSAASP ALSSGFEQPL RSPSLNASPG AAQTSAYDQS
YSQYPGQLSN GGGSFSSASQ PPYPTATQMP VGPYYSPNEH NSLYNRGSRS NSQASPMGSP
ANPGSASPGL QRHPTNAPLP SRPVDDELTW SAGHERITSD NLMQELELEL GGSGQGYRPL
PEPENGHYDD DLHGQRLQRF DSGATTIPNN ASRTTSTRTG QTAYEPEEED DDAYGEAGLM
AMRQAELDEQ RFSTGFGYTD MPAMPEPSPE PAPINSLSTK TLHTHPEEQG HSSDSDFAGV
DLGMLGGGFG GTLTYGGDVG SPPASSGQDT GRPLPTPGYF NRAYDQGESV PAFKTAEIDY
GGTGGLQPPT QHRLSFDEED ERVSLRSRQS GTESPSKDEL QDLFYHPGLS NRPLPAIPGP
GSDSSSMLSV QTNNRQQYQH AYSRSTDSRF GAPDNPEAYY TGNQAYNLQP ERSISLAGHS
HTPQVQTPAR SRTDAAEERR KLARHGHQQA PSNQSFPEYE TPAGSIAAFD GITLPSGRKK
KFIPSKLNAS DFRRCTEPWA LSGLETWIRE MGEGEMDLRT KTIEEALINL FTGKIPMMNV
ADAEVLSTHV VSLMLERGVL VPDEEWVKFG NGRISGVLWQ LTGSGCYAPK VHDEEIGGRC
YSHHCTRTLK KVDLEELAQD SQPADEWHVF YGLTKADWES KPKKEVERQN ILHEIVTGEE
NYIKQLDIFR RYYRDQLRAM QPPILKPEKR DKFLHTVFGK LDQVQAINKD HLLSQLKYRQ
QEQGPWIIGF SDLFREWIRK AKSVYIEYAS AYPNAVYQVR READRNILFK RFLDDMQKQK
VSSKQDWTHY LIAPIQRLQR YSLLLDSVEK KMPTDSEEKT NLAKAIAEIR QVTLESDTKV
EEQNKRVQMM ELNRMLVLRP GFHSVLNLDH LGRELIFQGD LQRMGSKGVR WVDTHALLFD
HYMILAKTVT PKEGKDKKYD VSKEPIPMPL LFPESINDEP VQKQKGITAP LGRTTAAAAS
STQLNKVSSN TGRPGLEHAA TNSSIGSGLT PTGSNDTEGK ILYPFKVKHL GHEVYTLYAS
SAKDRADWCN MIIETKTRHA KALFSQNAEP FRLRVLADAA FHYDTASMYA RFPSVAVKGT
PLDRAIHELE SVLGPAQGVA PVCRAQVNCA TSFTAFGKSV IAIGTDYGVY ISEPSNPRGW
QRTVQATRVT QIAVLEEFSV CVLIADKNLI SYPLDVIAPV SDFSAPLNDN PRRAPQRLAK
DVTYFATAKM KDRMLLFYKR KEGLHTSFKV LEPIFQKSTE KKSRLFGGRK TGGGGCAETF
RDFDEFFFPT ECYSLSLFQT YIAVATAKGV EMLTLDKKQP MSIPDLKAPA IANIASRIRD
QKPLGMFRLN ENEFIVTYED CAVYVDKHGD VSRTLIMEYT GKQKKARGAT MYGQYLLLFN
EDYVEVRNAE NGRLRQIIAG RDVRVLDLGV RGPTGRSTLN PQSHSNGYMQ STSAGSEGSK
GTVKIAMAHP ELPGRQIVLE MLLNDGHTEK
//
