ID W9QG46_9ROSA Unreviewed; 393 AA.
AC W9QG46;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Chalcone synthase 9 {ECO:0000313|EMBL:EXB36843.1};
DE SubName: Full=Polyketide synthase 2 {ECO:0000313|EMBL:AOA48570.1};
GN Name=PKS2 {ECO:0000313|EMBL:AOA48570.1};
GN ORFNames=L484_003228 {ECO:0000313|EMBL:EXB36843.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB36843.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EXB36843.1}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schn.";
RL Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AOA48570.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=27487946; DOI=10.1186/s12864-016-2843-7;
RA Li H., Liang J., Chen H., Ding G., Ma B., He N.;
RT "Evolutionary and functional analysis of mulberry type III polyketide
RT synthases.";
RL BMC Genomics 17:540-540(2016).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
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DR EMBL; KU596030; AOA48570.1; -; mRNA.
DR EMBL; KE343597; EXB36843.1; -; Genomic_DNA.
DR RefSeq; XP_010088676.1; XM_010090374.1.
DR AlphaFoldDB; W9QG46; -.
DR STRING; 981085.W9QG46; -.
DR GeneID; 21386771; -.
DR KEGG; mnt:21386771; -.
DR eggNOG; ENOG502QSSY; Eukaryota.
DR OrthoDB; 883077at2759; -.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF10; TYPE III POLYKETIDE SYNTHASE B; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 2: Evidence at transcript level;
KW Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW Transferase {ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 13..230
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 240..389
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 166
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 393 AA; 43302 MW; 4C2B52F45D8062BE CRC64;
MGSLDDARLT SPKKATPGKA TILALGKAFP HQLVMQEYLV DGYFRDTNCD DPELKRKLTR
LCKTTTVKTR YVVMSEEILK KYPELALEGR STVKQRLDIC NDAVTQMAIE ASQACIKNWG
RPVSDITHLV YVSSSEIRLP GGDLYLASGL GLSPETQRVM LYFVGCSGGV AGLRVAKDIA
ENNPGSRILL ATSETTIIGY KPPSADRPYD LVGVALFGDG AGAMIIGSDP VSETEKPLFE
LHSAMQRFLP GTDKTIDGRL TEEGISFKLA RELPQVIEDS VEGFCEKLMG VKGFDKEWYN
KMFWAVHPGG PAILNRIEKR LDLDPEKLNA SRKALMDYGN ASSNTIVYVL EYMLEESSKM
KVDQEENEWG LILAFGPGIT FEGILARNLT TTV
//
