ID W9R4K4_9ROSA Unreviewed; 558 AA.
AC W9R4K4;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=L484_024681 {ECO:0000313|EMBL:EXB68667.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB68667.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Might act as an E3 ubiquitin-protein ligase, or as part of E3
CC complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating
CC enzymes and then transfers it to substrates.
CC {ECO:0000256|ARBA:ARBA00003976}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the RBR family. Ariadne subfamily.
CC {ECO:0000256|ARBA:ARBA00005884}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE344580; EXB68667.1; -; Genomic_DNA.
DR RefSeq; XP_010097476.1; XM_010099174.1.
DR AlphaFoldDB; W9R4K4; -.
DR STRING; 981085.W9R4K4; -.
DR eggNOG; KOG1815; Eukaryota.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd20346; BRcat_RBR_ANKIB1; 1.
DR CDD; cd22583; Rcat_RBR_ARI7-like; 1.
DR CDD; cd23141; RING-HC_ARI6-like; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR048962; ARIH1-like_UBL.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685:SF444; E3 UBIQUITIN-PROTEIN LIGASE ARI7-RELATED; 1.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF21235; ARI1_UBAl; 1.
DR Pfam; PF01485; IBR; 2.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 186..399
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 190..234
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT COILED 400..427
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 558 AA; 63866 MW; B13AF80639032EFA CRC64;
MDNNNVWTHK KQKHPKWVVG ESQLIAFISR QRTPDRRLGF RAGELSTPAM DSEDDMHDAN
DMESVDEDDE GFYSDEMGFD YYCSDDDADV DYVVEDDSED FERIQSRRPE NNYIILKDSD
IEQRQEDDIT SVSTVLSISR DTACILLRHC NWSVSKVHEA WFADEERVRK AVGLLEEPVI
WFPNYRELTC GICFESFPRG RIKSAACGHP FCSACWAGYI STSINDGPGC LLLRCPDPSC
GAAVGRDMIN SLVSDEDLRK YSRYLHRSYI EDNKKTKWCP APGCDYAVNF VGDNENYDVS
CLCTYGFCWN CTEEAHRPVD CVTVAKWILK NSAESENMNW ILANSKPCPK CKRPIEKNQG
CMHMTCTPPC KFEFCWLCLG AWADHGERTG GFYACNRYEA AKQEGAYDEA ERRREMAKNS
LERYTHYYER WASNQLSRQK ALADLHLMQT VHMEKLSETQ SQPESQLKFI TEAWQQLPTP
LLLPIVKSTM ACSGDRRPFF DDHFLASGDI FSAVGPGDRW QFVLPDLVPE KGGDLLHCHR
TLVRVGGDFV EINSKKAF
//
