ID   W9RF58_9ROSA            Unreviewed;      1194 AA.
AC   W9RF58;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   ORFNames=L484_011630 {ECO:0000313|EMBL:EXB88201.1};
OS   Morus notabilis.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX   NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB88201.1, ECO:0000313|Proteomes:UP000030645};
RN   [1] {ECO:0000313|Proteomes:UP000030645}
RP   NUCLEOTIDE SEQUENCE.
RA   He N., Zhao S.;
RT   "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probably involved in the RNA silencing pathway and required
CC       for the generation of small interfering RNAs (siRNAs).
CC       {ECO:0000256|RuleBase:RU363098}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
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DR   EMBL; KE344949; EXB88201.1; -; Genomic_DNA.
DR   RefSeq; XP_010101266.1; XM_010102964.1.
DR   AlphaFoldDB; W9RF58; -.
DR   STRING; 981085.W9RF58; -.
DR   GeneID; 21394878; -.
DR   KEGG; mnt:21394878; -.
DR   eggNOG; KOG0988; Eukaryota.
DR   OrthoDB; 5477883at2759; -.
DR   Proteomes; UP000030645; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProtKB-KW.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF18; RNA-DEPENDENT RNA POLYMERASE 6; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   RNA-mediated gene silencing {ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ   SEQUENCE   1194 AA;  136814 MW;  04AF500A6D97BCA7 CRC64;
     MELEGSEKDT VVTQISIGGF DRHVKAKDLM DFLEYEVGIV YRCRLKTSCT ARESYPTFEN
     INSENIMESI DIRQVEPHAF VHFASPESVN WTLSNPLMLN NQTLKVTLGP ETLYRMNQRR
     RTTTPIKLAD VIVEIGNLVR RDEFFVAWRG PSYGVDFLVD PFDGLCKFCF TRDTAFSFKD
     MAKLAMMKCD FKVEFLVRDI NEIKQYTDTS HLVVLLLLAS SPRVWYRTAD DDIEVSVPFD
     LLDDDDPWIR TTDFTPSGAI GRCNSYRVSI PPRHGSKLKK AMSYLRERRV QETPLRKALR
     IQSEPDFAVP MSDPIFYVHG KHGIPFEIMF LLNVIVHKGI FNQHNISDGL FDLFRNQPRE
     INLAALKHIS SYKRPVFDAY AKLKNVQEWL LRNPKLLKIP RQLDDIAEVR RLVITPTRAY
     CLPPEVELSN RVLRKYKEVS DRFLRVTFMD EGMQTMNLNV LTYYPAPIVK ELTSNSTSQK
     TKVFKRVKSL LTDGFYLCGQ RYSFLAFSSN QLRDRSAWFF AEDGKITVNG IKKWMGRFNN
     RNIAKCAARM GQCFSSTYAT VEVPLTEVNF DLEEIERNTY VFSDGIGMIT PDLAKEVAEK
     LKLDINPPSA YQIRYAGCKG VVACWPPKGD GIRLSLRRSM NKFDSKHTIL EICSWTRFQP
     GFLNRQIVTL LSTLNVRDEI FWKMQETMLF KLNQMLTDAD VAFNVLTASC PEQGNVGAIM
     LSAGFKPQSE PHLQGMLTCI RAAQLWGLRE KARIFVPLGR WLMGCLDELG VLEQGQCFIQ
     VSTPSLENCF SKHGSRFSET KNNLEVIKGF VVIAKNPCLH PGDIRILEAV DVPGLHHLYD
     CLVFPQKGDR PHANEASGSD LDGDLYFVTW DENLIPPSKK SWNPMQYDPA KPRTLPRDVT
     QKDIIDFFSR NMVNESLGAI CNAHVVHADL SDYGALDEKC LSLAELAAIA VDFPKTGIIV
     TMPAHLKPKI YPDFMGKEEY QSYKSTKIMG RLYRQIKDEY SDDVSPSSEL NIVSSNIPFD
     TDLEVPGAAD FLDDAWEKKC SYDGQLKGLM IQYKVKREEE VVTGQIWSMP KHNSRKEGDL
     KERLKHSYTG LRKEFRQVFE KVDSDFEQLT DDEKNVLYEK RASAWYQITY HPKWVKKSQD
     MHDQLEEVKN VVMLSFAWIA ADYLARIKIR CRGVGDADST KPINSLGKYL ADRI
//