ID W9RHD2_9ROSA Unreviewed; 1044 AA.
AC W9RHD2;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=isoleucine--tRNA ligase {ECO:0000256|ARBA:ARBA00013165};
DE EC=6.1.1.5 {ECO:0000256|ARBA:ARBA00013165};
DE AltName: Full=Isoleucyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00032665};
GN ORFNames=L484_023524 {ECO:0000313|EMBL:EXB74782.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXB74782.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363035}.
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DR EMBL; KE344659; EXB74782.1; -; Genomic_DNA.
DR RefSeq; XP_010098278.1; XM_010099976.1.
DR AlphaFoldDB; W9RHD2; -.
DR STRING; 981085.W9RHD2; -.
DR eggNOG; KOG0433; Eukaryota.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004822; F:isoleucine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0006428; P:isoleucyl-tRNA aminoacylation; IEA:InterPro.
DR GO; GO:0009791; P:post-embryonic development; IEA:UniProt.
DR GO; GO:0048608; P:reproductive structure development; IEA:UniProt.
DR CDD; cd07960; Anticodon_Ia_Ile_BEm; 1.
DR CDD; cd00818; IleRS_core; 1.
DR Gene3D; 1.10.730.20; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 2.
DR Gene3D; 1.10.10.830; Ile-tRNA synthetase CP2 domain-like; 1.
DR Gene3D; 3.90.740.10; Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain; 1.
DR HAMAP; MF_02002; Ile_tRNA_synth_type1; 1.
DR InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR InterPro; IPR002300; aa-tRNA-synth_Ia.
DR InterPro; IPR033708; Anticodon_Ile_BEm.
DR InterPro; IPR002301; Ile-tRNA-ligase.
DR InterPro; IPR023585; Ile-tRNA-ligase_type1.
DR InterPro; IPR013155; M/V/L/I-tRNA-synth_anticd-bd.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR InterPro; IPR009008; Val/Leu/Ile-tRNA-synth_edit.
DR InterPro; IPR010663; Znf_FPG/IleRS.
DR NCBIfam; TIGR00392; ileS; 1.
DR PANTHER; PTHR42765:SF1; ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42765; SOLEUCYL-TRNA SYNTHETASE; 1.
DR Pfam; PF08264; Anticodon_1; 1.
DR Pfam; PF00133; tRNA-synt_1; 2.
DR Pfam; PF06827; zf-FPG_IleRS; 1.
DR PRINTS; PR00984; TRNASYNTHILE.
DR SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR SUPFAM; SSF50677; ValRS/IleRS/LeuRS editing domain; 1.
DR PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000256|RuleBase:RU363035};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363035};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363035};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363035};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW ECO:0000256|RuleBase:RU363035};
KW Reference proteome {ECO:0000313|Proteomes:UP000030645}.
FT DOMAIN 105..159
FT /note="Aminoacyl-tRNA synthetase class Ia"
FT /evidence="ECO:0000259|Pfam:PF00133"
FT DOMAIN 161..723
FT /note="Aminoacyl-tRNA synthetase class Ia"
FT /evidence="ECO:0000259|Pfam:PF00133"
FT DOMAIN 768..931
FT /note="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase
FT anticodon-binding"
FT /evidence="ECO:0000259|Pfam:PF08264"
FT DOMAIN 1002..1030
FT /note="Zinc finger FPG/IleRS-type"
FT /evidence="ECO:0000259|Pfam:PF06827"
SQ SEQUENCE 1044 AA; 117518 MW; 6C97EE984012A3AB CRC64;
MAVLSTSPYR VLSKRTCSSF RKNSLSSFHP KGSYLFTLFN MKHYSNYSSD EFNSSKRRSR
GPVMAAKKAA EGGKQEDGKY KHTVDLPKTT FGMRANSLVR EPELHKIWDD NEVFKRVVDK
NSGGNFILHD GPPYANGDLH MGHALNKILK DMINRYKSLD ETTRKDLTPI KLRAKAAKFA
KGTVKTQMES FKRYGVWADW DNPYLTLDPE YEAAQIEVFG QMAIQGYIYR GRKPVHWSPS
SRTALAEAEL EYPEGHVSRS IYAIFRLVTA PPVLGGILNE YLPNLCLAIW TTTPWTIPAN
AAVAVNAKLQ YAIVEVQTLS EDASLSAGSK KRQLRNVLKE KKKPFLIVAL DLVPTLEAKW
SVKLVVRKTL SGSDIENCRY IHPISNKECP VVVGGDYITT ESGTGLVHTA PGHGQEDYVT
GLKYGLPILS PVDDDGKFTE EAGQFNGLDV LADGNVAVVK YLDENLSLIM EEPYAHKYPY
DWRTKKPTIF RATEQWFASV EGFRQSAMDA IGHVKWIPAQ AENRISAMTS SRSDWCISRQ
RTWGVPIPVF YHVQTKEPLM NEETIDHIKS IIAQKGSDAW WYMKVEDLLP GKYRDKASEY
VKGTDTMDVW FDSGSSWAAV LGRRNGLSFP ADLYVEGTDQ HRGWFQSSLL TSIATKGQAP
YSSVITHGFV LDEKGLKMSK SLGNVVDPQS VIVGGKNQKE APGYGADVLR LWVSSVDYTG
DVMIGPQVLR QMSDIYRKLR GTLRYLLGNL HDWHADNAVP YHDLPMIDRH ALFQLENVVT
SIRESYENYQ FFKIFQVIQR FVIVDLSNFY FDVAKDRLYV GGTTSSTRRS CQTVLEAHLL
SIVRVIAPIL PHLAEDVWQN LPFKYTKEDG SIAEFVFESS WPASNKTRLS FPAEEVDFWE
KILELRTEVN KVLEVARTGK LIGSSLEAKV YLHTSDARLA SRLREMCEAN NDADTLHRIF
ITSQAEILPS MENELTGNVP HTGECLIQGK TKVWIGVSRA EGGKCERCWN FSLQVGSFSE
HPTLCSRCYN AVSVQHFPAV AMAT
//
