ID W9RVH4_9ROSA Unreviewed; 317 AA.
AC W9RVH4;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Methyl-CpG-binding domain-containing protein 2 {ECO:0000313|EMBL:EXC12834.1};
GN ORFNames=L484_008228 {ECO:0000313|EMBL:EXC12834.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXC12834.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KE345724; EXC12834.1; -; Genomic_DNA.
DR RefSeq; XP_010106952.1; XM_010108650.1.
DR AlphaFoldDB; W9RVH4; -.
DR STRING; 981085.W9RVH4; -.
DR GeneID; 21391601; -.
DR KEGG; mnt:21391601; -.
DR eggNOG; KOG4161; Eukaryota.
DR OrthoDB; 1217115at2759; -.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd01396; MeCP2_MBD; 1.
DR Gene3D; 3.30.40.100; -; 1.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR InterPro; IPR011124; Znf_CW.
DR PANTHER; PTHR12396:SF0; METHYL-CPG BINDING DOMAIN PROTEIN-LIKE, ISOFORM C; 1.
DR PANTHER; PTHR12396; METHYL-CPG BINDING PROTEIN, MBD; 1.
DR Pfam; PF01429; MBD; 1.
DR Pfam; PF07496; zf-CW; 1.
DR SMART; SM00391; MBD; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR PROSITE; PS50982; MBD; 1.
DR PROSITE; PS51050; ZF_CW; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 92..151
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT DOMAIN 157..231
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT REGION 1..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..305
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 317 AA; 35616 MW; D8464F0619A8F89F CRC64;
MTENNFHDSS FLSQGDNTSQ DFIDVSSSSS SSDDESSEDE NNQSGDASKQ LVLYDPAANG
TLVPAPEPAT PFQQHPRRQG FPISNQQSPR VLPSVGAFTV QCANCFKWRL IPTKEKYEEI
REHILEQPFY CETAREWRPD ISCDDPADIS QDGSRLWAID KPNIAQPPPG WQRLLRIRGE
GSTKFADVYY VAPSGKRLRS MVEVQKYLLE HPEYVSNGVT MSQFSFQIPK PLQENYVRKR
PARLLASCNG NERLEPDLVR PLAWAGPDES PDLQLGMPRL PPPCVPDPIN RPAKKRAKKS
PPKEMYSSDP RASIDSS
//
