ID W9S956_9ROSA Unreviewed; 580 AA.
AC W9S956;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Protein HOTHEAD {ECO:0000313|EMBL:EXC17781.1};
GN ORFNames=L484_023132 {ECO:0000313|EMBL:EXC17781.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXC17781.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; KE345823; EXC17781.1; -; Genomic_DNA.
DR RefSeq; XP_010108049.1; XM_010109747.1.
DR AlphaFoldDB; W9S956; -.
DR STRING; 981085.W9S956; -.
DR eggNOG; KOG1238; Eukaryota.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0046593; F:mandelonitrile lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.30.410.40; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR45968:SF3; OS04G0573100 PROTEIN; 1.
DR PANTHER; PTHR45968; OSJNBA0019K04.7 PROTEIN; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR000137-3};
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000137-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 282..296
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 124
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 237
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 514..515
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 543
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 554..555
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT DISULFID 451..506
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-3"
SQ SEQUENCE 580 AA; 63012 MW; 5BB7A38824D7604A CRC64;
MEDNIGRWRL FAAALTGSIF FFFSSLSAAQ KGPNYTFMHN ATTAPDISYY DYIIVGGGTA
GCPLAATLSQ NYSVLLLERG GSPYGNPNIT NLSAFGAALS DTSPTSPSQR FISEDGVINS
RARVLGGGSC LNAGFYTRAG TDYVREVGWD GRLVNESYHW VERVVAFEPP MGQWQSAVRD
GLLEVGVQPY NGFTYDHIVG TKVGGTIFDR DGHRHTAADL LQYANPTGLT VLLHATVHKV
LFRTKGRQRP SAHGVAFRDA SGIRHRAYLT NGPRSEIIIS SGALGSPQLL MLSGVGPAQH
LQAHNITVVL DQPMVGQGMS DNPMNSIFIP SPIPVEVSLI EVVGITGFGS YIEAAGGENF
AGGNPRDYGM FSPKIGQLAT VPPKERTPEA LARAVQLMDS LEDAAFRGGF LLEKIMGPIS
TGHLELRTRN PNDNPAVTFN YFKETLDLQR CVQGISTIER IIESKSFSRF RYDYMSVPTL
LNMTASSPIN LLPKHANSST SLEQFCKDTV MTIWHYHGGC QVGRVVDTDY KVLGVDALRV
IDGSTFSYSP GTNPQATVMM LGRYMGVRIL GERLDAEESK
//
