ID W9SG16_9ROSA Unreviewed; 768 AA.
AC W9SG16;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Subtilisin-like protease {ECO:0000313|EMBL:EXC04834.1};
GN ORFNames=L484_010262 {ECO:0000313|EMBL:EXC04834.1};
OS Morus notabilis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Moraceae; Moreae; Morus.
OX NCBI_TaxID=981085 {ECO:0000313|EMBL:EXC04834.1, ECO:0000313|Proteomes:UP000030645};
RN [1] {ECO:0000313|Proteomes:UP000030645}
RP NUCLEOTIDE SEQUENCE.
RA He N., Zhao S.;
RT "Draft Genome Sequence of a Mulberry Tree, Morus notabilis C.K. Schneid.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; KE345511; EXC04834.1; -; Genomic_DNA.
DR RefSeq; XP_010105478.1; XM_010107176.1.
DR AlphaFoldDB; W9SG16; -.
DR GeneID; 21393557; -.
DR KEGG; mnt:21393557; -.
DR eggNOG; ENOG502QSVG; Eukaryota.
DR OrthoDB; 11910at2759; -.
DR Proteomes; UP000030645; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR GO; GO:0009610; P:response to symbiotic fungus; IEA:UniProt.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF388; XYLEM SERINE PROTEINASE 1; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000030645};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..768
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004933167"
FT DOMAIN 35..110
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 135..589
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 385..459
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 660..764
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT REGION 203..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 142
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 215
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 545
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 768 AA; 81223 MW; 8303288058C5A8F3 CRC64;
MKTPIFIILQ LSAVLLSICQ LHVAADGRQS QQKRTYIIHM DKSNKPATFD NHFNWYDSSL
KSVSDSADML YTYNNVIHGF STSLTEKEAQ FLKQQPGVLS VLQENRYELH TTRTPEFLGL
GRSDALFPAS DKLSEVIVGV LDTGVWPESK SYDDAGLRRV PSSWKGECEV GKNFNSSSCN
MKLIGARYFS AGYEEAFGPI DEKVESKSPR DDDGHGTHTS TTAAGSTVVE ASLFGFASGT
ARGMATTARV ATYKVCWLGG CFGSDILAGI DKAIDDGVDV LSLSIGGGLN DYYRDTVAIG
TFAAVAHGIV VSVSAGNGGP GSGSLSNVAP WLTTVGAGTL DRDFPAYVSL GNGQKYKGVS
LYSGKPLSEE LVQIVYGRTA NNSTNGNLCL PGSLDSAKVT GKLVVCDRGG NPRAQKGQVV
KDAGGVGMIL SNTESYGEEL VADAHLLPAV TVGQRTGNLI KTYLRSDANP TATITQGSTQ
LGIQPSPVVA AFSSRGPNPI TPEILKPDLI APGVNILAGW TGRAGPTGLD TDNRRVSFNI
VSGTSMSCPH VSGLAALLKA AHPEWSPAAI RSALMTTAYS TYKGGKTISD ISTGSSATPF
DYGAGHVDPV AALEPGLVYD ATVQDYISFF CALNYSASQI KTVTKGDYTC DHTKKYSLGD
FNYPSFAVPL ETASSSEGGA DASSTVKYTR TLTNVGEPAT YKVSISSDPS VKISVQPESL
SFSEAYEKKT YTVTFTANSQ PSGTTSFARL EWSDGKHAVS SPIAFSWT
//
