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Database: UniProt
Entry: W9UZ94_9GAMM
LinkDB: W9UZ94_9GAMM
Original site: W9UZ94_9GAMM 
ID   W9UZ94_9GAMM            Unreviewed;       526 AA.
AC   W9UZ94;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   05-JUL-2017, entry version 26.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:EXJ10031.1};
GN   ORFNames=D791_03004 {ECO:0000313|EMBL:EXJ10031.1};
OS   Nitrincola nitratireducens.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Nitrincola.
OX   NCBI_TaxID=1229521 {ECO:0000313|EMBL:EXJ10031.1, ECO:0000313|Proteomes:UP000019464};
RN   [1] {ECO:0000313|EMBL:EXJ10031.1, ECO:0000313|Proteomes:UP000019464}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AK23 {ECO:0000313|EMBL:EXJ10031.1,
RC   ECO:0000313|Proteomes:UP000019464};
RA   Singh A., Pinnaka A.K., Vaidya B.;
RL   Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EXJ10031.1}.
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DR   EMBL; AONB01000017; EXJ10031.1; -; Genomic_DNA.
DR   RefSeq; WP_036512747.1; NZ_AONB01000017.1.
DR   EnsemblBacteria; EXJ10031; EXJ10031; D791_03004.
DR   PATRIC; fig|1229521.3.peg.3033; -.
DR   Proteomes; UP000019464; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000019464};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019464}.
FT   DOMAIN      223    354       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      434    503       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     231    238       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   526 AA;  58979 MW;  D84145511A6683FE CRC64;
     MSDELWERCL SSLRDEFPAQ QYNTWIRPLR LAQCQTDLLV LLAPNRFVKD WVSDKYLSHI
     RQAFSHLTGS ISAEVMIEIA QSGSAQPLLR PSNPVASVPV AQTTDARSPA PVTPTVLSND
     PVYVPAQEAH YSESLSTTSY DIPSVGSESA SDMQAMPEPQ LELEMLPAED TRKRKPRKVD
     VEGGVKHQSN LNPAFTFQAF VQGKSNQLAL AAAQQVADNP GGGYNPLFIY GGVGLGKTHL
     MHAVGCEMLR RNPNARILYL HSERFVADMV KALQLNAFND FKRYYRSVDA LLIDDIQFFA
     GKERSQEEFF HTFNALLEGG QQLILTSDRY PKEISGVEER LKSRFGWGLT VPIEPPELET
     RVAILMKKAQ EARIQLPHDS AFFLAQKIRS NVRELEGALK RVIANAHFTG STISTPFIKE
     SLKDLLALQD KQVSIDNIQR VVAEYYKIKI ADLLSKRRSR SVARPRQVAM SISKELTNHS
     LPEIGNAFGG RDHTTVLHAC RKIKELRETD ADISEDYKNL LRHLTA
//
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