ID   W9W5T4_9EURO            Unreviewed;       811 AA.
AC   W9W5T4;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   28-JUN-2023, entry version 21.
DE   SubName: Full=Phosphoketolase 1 {ECO:0000313|EMBL:EXJ60340.1};
GN   ORFNames=A1O7_04492 {ECO:0000313|EMBL:EXJ60340.1};
OS   Cladophialophora yegresii CBS 114405.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=1182544 {ECO:0000313|EMBL:EXJ60340.1, ECO:0000313|Proteomes:UP000019473};
RN   [1] {ECO:0000313|EMBL:EXJ60340.1, ECO:0000313|Proteomes:UP000019473}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 114405 {ECO:0000313|EMBL:EXJ60340.1,
RC   ECO:0000313|Proteomes:UP000019473};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Cladophialophora yegresii CBS 114405.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000256|ARBA:ARBA00005623}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXJ60340.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AMGW01000003; EXJ60340.1; -; Genomic_DNA.
DR   RefSeq; XP_007756693.1; XM_007758503.1.
DR   AlphaFoldDB; W9W5T4; -.
DR   STRING; 1182544.W9W5T4; -.
DR   GeneID; 19179078; -.
DR   VEuPathDB; FungiDB:A1O7_04492; -.
DR   eggNOG; ENOG502QUUF; Eukaryota.
DR   HOGENOM; CLU_013954_2_0_1; -.
DR   OrthoDB; 5485390at2759; -.
DR   Proteomes; UP000019473; Unassembled WGS sequence.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd02011; TPP_PK; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PHOSPHOKETOLASE-RELATED; 1.
DR   PANTHER; PTHR31273:SF0; PHOSPHOKETOLASE-RELATED; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019473};
KW   Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}.
FT   DOMAIN          29..390
FT                   /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT                   phosphoketolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09364"
FT   DOMAIN          608..809
FT                   /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT                   phosphoketolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09363"
SQ   SEQUENCE   811 AA;  91218 MW;  EEF6C394C17BF602 CRC64;
     MGSVVEGDVS VESISPFGKA RSTIKDAPLS EEELKLTDDY MRASLYLCLG MLYLRQNPLL
     KEPLKVEHLK ARLLGHWGSD AGQIFTYVAM NRLIKKYDLD VIFISGPGHG APAVISQAYL
     EGVYSEVYPD KSEDVEGLRK FFKQFSFPGG IGSHATPETP GSLHEGGELG YSISHAFGTV
     FDHPDLIALT MVGDGESETG PLATSWHSTK FLNPITDGAV LPVLHLNGYK INNPTLLARI
     SHRELEALFV GYGWTPYFVE GSDPLSMHQA MAATLEKAVQ DIRGYQKKAR ESGKAFRPLW
     PMIILRSPKG WTGPRTVDGH YLEGYWRAHQ IPLPNVASSP EHLKLLEEWM KSYTPEKYFT
     EDGKLVPELK KVAPEGNRRM SANPVANGGL IKKPLLMPDF REYSLPVEKG GIKDAPSMSN
     FANFLRDIIQ KNPHNFRLFG PDETESNKLG GVYAAGKKVW LGEYFDEDAD GGNLAFEGRV
     MEMLSEHTVE GWLEGYLLSG RHGMLNSYEP FIHIIDSMVN QHCKWIEKCL EVEWRAKIAS
     LNILLTATVW RQDHNGFTHQ DPGFLDVVCN KSPEVVRIYL PPDGNCLLSV MDHCFRSSNY
     VNVIVADKQN HLQYLDTEAA IEHCTKGAGI WDWASNDQGE EPDVVMASCG DVPTMEALAA
     TALLREYIPE LKIRFVNVVD LFKLIPHGDH PHGMTQRDFE AIFTPNKPVI FNFHSYPWLI
     HRLTAQRPSQ HNLHVRGYNE KGNIDTPLEL AIRNRTDRFS LAMEALDRMP ELGNKGSSAR
     EKLLSSQIKY RTVAFNEGID PEEIRTWKWP F
//