ID W9W6Q2_9EURO Unreviewed; 381 AA.
AC W9W6Q2;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 28-JUN-2023, entry version 21.
DE SubName: Full=5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase {ECO:0000313|EMBL:EXJ60675.1};
GN ORFNames=A1O7_04828 {ECO:0000313|EMBL:EXJ60675.1};
OS Cladophialophora yegresii CBS 114405.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182544 {ECO:0000313|EMBL:EXJ60675.1, ECO:0000313|Proteomes:UP000019473};
RN [1] {ECO:0000313|EMBL:EXJ60675.1, ECO:0000313|Proteomes:UP000019473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114405 {ECO:0000313|EMBL:EXJ60675.1,
RC ECO:0000313|Proteomes:UP000019473};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora yegresii CBS 114405.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ60675.1}.
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DR EMBL; AMGW01000003; EXJ60675.1; -; Genomic_DNA.
DR RefSeq; XP_007757028.1; XM_007758838.1.
DR AlphaFoldDB; W9W6Q2; -.
DR STRING; 1182544.W9W6Q2; -.
DR GeneID; 19179413; -.
DR VEuPathDB; FungiDB:A1O7_04828; -.
DR eggNOG; ENOG502QVN2; Eukaryota.
DR HOGENOM; CLU_058877_0_0_1; -.
DR OrthoDB; 5488137at2759; -.
DR Proteomes; UP000019473; Unassembled WGS sequence.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR43844; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR43844:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF01717; Meth_synt_2; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:EXJ60675.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000019473};
KW Transferase {ECO:0000313|EMBL:EXJ60675.1}.
FT DOMAIN 13..372
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 381 AA; 42653 MW; 74AA1AAB1B9F8481 CRC64;
MPLPTGVYRA DQVGSLLRPQ EILALREKIA KGEASISDLR PLEDKYIADV VRKQLDAGLR
AITDGEFRRG FFHLDFLQHL DGIEVRGQLM STNTSKGGFQ PPTLVVTGKL GHPKAIQVDD
FRFLERQIQE AGGAGKATTK VAIPSPTMVH FRGGRQTIDL DAYPSMDDFF DDLARVYQEE
VADLYAAGCR FLQLDDTNLA YLCDPKMRTE AEARHGSDAR QIASQYASLI NRAIEKRPAD
MTVGIHLCRG NHRSQWFAQG GYEPVAEVLF RDLNVDVYFL EYDDARSGDF SPLRHLPEDK
VVVLGVLTSK KGDLDDKDAI TQRLNEAAKY CKKGLDQLCV SHQCGFSSTM EGNELSEEQQ
WAKLRLEVEI AKKVWGDDLS K
//
