ID   W9WAE8_9EURO            Unreviewed;       560 AA.
AC   W9WAE8;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=FAD-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=A1O7_02392 {ECO:0000313|EMBL:EXJ61960.1};
OS   Cladophialophora yegresii CBS 114405.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=1182544 {ECO:0000313|EMBL:EXJ61960.1, ECO:0000313|Proteomes:UP000019473};
RN   [1] {ECO:0000313|EMBL:EXJ61960.1, ECO:0000313|Proteomes:UP000019473}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 114405 {ECO:0000313|EMBL:EXJ61960.1,
RC   ECO:0000313|Proteomes:UP000019473};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Cladophialophora yegresii CBS 114405.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- SIMILARITY: Belongs to the paxM FAD-dependent monooxygenase family.
CC       {ECO:0000256|ARBA:ARBA00007992}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXJ61960.1}.
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DR   EMBL; AMGW01000002; EXJ61960.1; -; Genomic_DNA.
DR   RefSeq; XP_007754614.1; XM_007756424.1.
DR   AlphaFoldDB; W9WAE8; -.
DR   STRING; 1182544.W9WAE8; -.
DR   GeneID; 19176999; -.
DR   VEuPathDB; FungiDB:A1O7_02392; -.
DR   eggNOG; KOG2614; Eukaryota.
DR   HOGENOM; CLU_009665_19_1_1; -.
DR   OrthoDB; 2678872at2759; -.
DR   Proteomes; UP000019473; Unassembled WGS sequence.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR002938; FAD-bd.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR13789:SF315; FAD-DEPENDENT MONOOXYGENASE MDPD; 1.
DR   PANTHER; PTHR13789; MONOOXYGENASE; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   Pfam; PF01494; FAD_binding_3; 1.
DR   PRINTS; PR00420; RNGMNOXGNASE.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019473}.
FT   DOMAIN          49..138
FT                   /note="FAD-dependent oxidoreductase 2 FAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF00890"
FT   DOMAIN          261..428
FT                   /note="FAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01494"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   560 AA;  61455 MW;  0B05C0FC2A47C606 CRC64;
     MGSLGSLTSP SSEGSPGSGY FVDGNPCDFD PEWWEPGTLP KRHPETHLDV LIVGAGLAGL
     MTALECWRRG HNVVGILERS HGPVYAGAFL PSHSNHHFIR GADVLTFGRP AGDIIVIGPS
     ATAAFRHWPD MMRELEADQH DSTMSYYTHN GELILGPTQL GFNDPKYMAE REGHPVTAPH
     QVRRKFFQML LRQVARVGLR VEYGQQVERY FEDEIARVGG VITKSGTIRV ADVVVAADAN
     KTKSALLIAG SHAPTQSAGM SVYRTSMPTE LAMQNDAFRA RWGAAIARNE ISHEFWTGPG
     IHMGLVVSPE FTAYGITPRD STVHNGGIQP IESWKPDVDP AEVIKVLQRL PDWDPAVLGL
     VSATPKGRII HWPLLWRNLR REWTSKGGHV VQVGEAAHSS LPASASGGTL AIEDAVTLAA
     CLQLSCAGGG GGRDGGGGGA RRAPTGTRIY NLLRYERVSC AQKMAFVNAE ALGDANMAEI
     RRHPEKIRVR FPEWLFHHDP EEYVYEKYGL AFAHVVLGRD KFVNTNLPPG HKFRPWTIEE
     VREDARSGKR VEDLLDGDWS
//