ID W9WKL4_9EURO Unreviewed; 388 AA.
AC W9WKL4;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN ORFNames=A1O7_01501 {ECO:0000313|EMBL:EXJ65161.1};
OS Cladophialophora yegresii CBS 114405.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182544 {ECO:0000313|EMBL:EXJ65161.1, ECO:0000313|Proteomes:UP000019473};
RN [1] {ECO:0000313|EMBL:EXJ65161.1, ECO:0000313|Proteomes:UP000019473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114405 {ECO:0000313|EMBL:EXJ65161.1,
RC ECO:0000313|Proteomes:UP000019473};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora yegresii CBS 114405.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ65161.1}.
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DR EMBL; AMGW01000001; EXJ65161.1; -; Genomic_DNA.
DR RefSeq; XP_007753728.1; XM_007755538.1.
DR AlphaFoldDB; W9WKL4; -.
DR STRING; 1182544.W9WKL4; -.
DR GeneID; 19176113; -.
DR VEuPathDB; FungiDB:A1O7_01501; -.
DR eggNOG; KOG1430; Eukaryota.
DR HOGENOM; CLU_007383_6_8_1; -.
DR OrthoDB; 1133at2759; -.
DR Proteomes; UP000019473; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019473}.
FT DOMAIN 24..296
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 388 AA; 42245 MW; 0F220D3177453F99 CRC64;
MEEDAEGVPV QPNTDIKAPR VKVVVTGGLG FVGSAVVRAL HEFHPDWHVW ILDKCNHAPG
ELDLLRGCKY EYVQANITDG DSVMRALSLI EPDAVVHTAG IVPSLSERYA RRLEALVHNT
NVEGTRHMVD AASKCGCRAF VYTSSCCAVT DDMSKSYANI DETWPVAERS SVYGESKAAA
ERIVIAANKD PNPMATCVLR PCVVFGEGDD QLIPPIHACI AKGETRWVIG SATNLWDTVY
VGNVADAHVL AVENLLQSET AAGETFFIQN NEPVSFRDFS LAVWKEFGHF PPAWEIPIPA
GLGWVLGLLA EVFTRVSGTP TTLSRGSVMD ACAMRYASGD KAKSILGYQP RVGLEDGIRW
SCQVSRASQV LRIATLTEVM PIRSMRDA
//
