ID W9WQ42_9EURO Unreviewed; 1323 AA.
AC W9WQ42;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=BRCT domain-containing protein {ECO:0000259|PROSITE:PS50172};
GN ORFNames=A1O7_04652 {ECO:0000313|EMBL:EXJ60499.1};
OS Cladophialophora yegresii CBS 114405.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182544 {ECO:0000313|EMBL:EXJ60499.1, ECO:0000313|Proteomes:UP000019473};
RN [1] {ECO:0000313|EMBL:EXJ60499.1, ECO:0000313|Proteomes:UP000019473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114405 {ECO:0000313|EMBL:EXJ60499.1,
RC ECO:0000313|Proteomes:UP000019473};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora yegresii CBS 114405.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ60499.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMGW01000003; EXJ60499.1; -; Genomic_DNA.
DR RefSeq; XP_007756852.1; XM_007758662.1.
DR STRING; 1182544.W9WQ42; -.
DR GeneID; 19179237; -.
DR VEuPathDB; FungiDB:A1O7_04652; -.
DR eggNOG; KOG3548; Eukaryota.
DR HOGENOM; CLU_002263_0_0_1; -.
DR OrthoDB; 1406366at2759; -.
DR Proteomes; UP000019473; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR CDD; cd17745; BRCT_p53bp1_rpt1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR047249; BRCT_p53bp1-like_rpt1.
DR InterPro; IPR041297; Crb2_Tudor.
DR InterPro; IPR047252; TP53BP1-like.
DR PANTHER; PTHR15321:SF3; TP53-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR15321; TUMOR SUPPRESSOR P53-BINDING PROTEIN 1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF18115; Tudor_3; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000019473}.
FT DOMAIN 1040..1146
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 32..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 454..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 660..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1000..1029
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1258..1285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..103
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..272
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..303
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..366
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 454..472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..520
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..573
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..605
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..632
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..761
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..787
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1000..1020
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1323 AA; 145372 MW; 43D48CCA01939223 CRC64;
MTTQSSSDAT QELSQSHYDL ILSKSRIEGQ LQEQEQNRAL HPVWQKDFER GDDAGGTQHE
GDTGFIDLMS SFENEKHDQE PEAAVEQTSD QDQRQRGTDS DDKEPEHEQE DSEPIEVDFS
PTQPTQSHAA LSQFPESQRF KTPVTAGKKR RYNGEIVESP DLPRNIRPLL RGGEDNAIPM
GLSQAFGATQ ANTSPFVGEL GNGRIDSDRP SPDIHLQQRP MTATSSSPLR PLSTIKRPDR
AGTEPLDHYI SSKESQARRE DARRKQLEDM YAEDGSPGED DLELQEDSWY ARDRRERERS
RRIQAQLTSS SPPVPSTRGV SISKSSPLRP PARRSSPIRM RASKQPRRNR ESSPPRPDPR
SQVTESEEET EQEDNKDIEP TASSQSSAPV DEEDKENVSD RAIQIPATTI DLHRLTQGPP
SQVQESPLLR RGLTFDEGGL SVALNSSQVF AVADSQPQRS IKPPQAVAQV TRSSVADDGP
DFVPQSPDTT PQPTAPISRN HPSTTLPTLT TGSTAEQQSD AVVDPVAPVS SPQARQPLSS
TIPETSSNEP RDQSGKASED TPRTCDAESR PEFETAGTHV QPPSSTVVHQ PTAVELSSPP
ISTTPPGRRR QRLLDIQGDP SPQKSQSSFD ATAHLRLEIH GSPTPMRTSV TAAIKTKLPD
LASEGARNGV SARGDVLHGA PESPEIQDEA KTGVEAQEQH GLQKQYVQPL SPVATFPERD
RRSTAKGLRA RSFETSRAGP RRRSSQYDLP ESSERRVNSA SKRTAKLKRK IQSTDNPSDR
APDANKRLKL TKSNSAPDVS LPSNPAQPQD DIPDHPALDN QNRVHDSHQL EGDNDVADGV
DEDLVAPNMV FAAFNGKSRT YYPALCLGRP ATDSGRFTIQ WEGYAPDEVD EYGVRSLDLR
VGDQVKIDME GFPKVSHVIR GFKDKISRGN VDSGQFVVTD IHGYQTLLVA PKQRKSLPVE
ISTEGVKKVP VSAIYLDTIM WGQMKDRVYE GKSSLYEARS MARSTPVPQI SSSSRPSPPP
SRSRRGVAVP VPPISSTIVR PNGLFSNMAF AVSHYDNPTK ARLVALVQEN GGSILEESFT
DLFEVDSIQL KDHYADVGFT ALLTDRHMRN VKYSQALALG LPCLSGRWIE ASVQTGRLAD
WSSYLLAAGE STELDGAVKS RLLQLPSSIQ GLELRDMLDL RAKILHNSRV VFVMGKGKTR
EDRKPTLFLI RALGPSQVIT ETHISGAKEI VQSAEQSKEP IDYVVVGDSE TRAAKKLFSS
EATTPRKEEK GHKKGRPKKG RVPGHLDTAA KQELDGVGER PQIICKADII QSLILGKLWI
GKT
//
