ID   W9X2Q3_9EURO            Unreviewed;       491 AA.
AC   W9X2Q3;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Amine oxidase {ECO:0000256|RuleBase:RU362067};
DE            EC=1.4.3.- {ECO:0000256|RuleBase:RU362067};
GN   ORFNames=A1O5_05022 {ECO:0000313|EMBL:EXJ71216.1};
OS   Cladophialophora psammophila CBS 110553.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Cladophialophora.
OX   NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ71216.1, ECO:0000313|Proteomes:UP000019471};
RN   [1] {ECO:0000313|EMBL:EXJ71216.1, ECO:0000313|Proteomes:UP000019471}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ71216.1,
RC   ECO:0000313|Proteomes:UP000019471};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a secondary aliphatic amine + H2O + O2 = a primary amine + an
CC         aldehyde + H2O2; Xref=Rhea:RHEA:26414, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15379, ChEBI:CHEBI:16240, ChEBI:CHEBI:17478,
CC         ChEBI:CHEBI:58855, ChEBI:CHEBI:65296; EC=1.4.3.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00000205};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974,
CC         ECO:0000256|RuleBase:RU362067};
CC   -!- SIMILARITY: Belongs to the flavin monoamine oxidase family.
CC       {ECO:0000256|ARBA:ARBA00005995, ECO:0000256|RuleBase:RU362067}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXJ71216.1}.
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DR   EMBL; AMGX01000007; EXJ71216.1; -; Genomic_DNA.
DR   RefSeq; XP_007743815.1; XM_007745625.1.
DR   AlphaFoldDB; W9X2Q3; -.
DR   STRING; 1182543.W9X2Q3; -.
DR   GeneID; 19189742; -.
DR   eggNOG; KOG0029; Eukaryota.
DR   HOGENOM; CLU_004498_9_0_1; -.
DR   OrthoDB; 5471885at2759; -.
DR   Proteomes; UP000019471; Unassembled WGS sequence.
DR   GO; GO:0097621; F:monoamine oxidase activity; IEA:RHEA.
DR   Gene3D; 3.90.660.10; -; 2.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR001613; Flavin_amine_oxidase.
DR   PANTHER; PTHR43563; AMINE OXIDASE; 1.
DR   PANTHER; PTHR43563:SF1; FLAVIN-CONTAINING MONOAMINE OXIDASE B-RELATED; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   PRINTS; PR00757; AMINEOXDASEF.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|RuleBase:RU362067};
KW   Flavoprotein {ECO:0000256|RuleBase:RU362067};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU362067};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019471}.
FT   DOMAIN          49..475
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
SQ   SEQUENCE   491 AA;  55191 MW;  412E848327D0E9F2 CRC64;
     MHKSREGWHW TPDTGLQAGI PSIAVIEPSQ LIRNSKDIFD VIVIGAGYTG LTAARDTSTT
     GLKTLLLEGR DRIGGRTWSS EIDGYPYEMG GTWVHWFQPH VYRELSRYGM KDHLVHSTDY
     TKKHNFFTLR TSAGARNMSH EEEDELFARA VGKFVNVDGD FGKTVMPFPF SAYSNEDVFK
     YANLSVADRI AQISHDLSSD ERHAVEAFVL LCSGGTTENS AFLDFLRWWA AANYDYKTLL
     DTIIVFKLKC GQSGFAKRFF EEALASGNLS YSFSNPVAHI DSSKGLVQMR TKDGQYFSAK
     KVICTAPLNV LEEIEFNPPL DRAKREAASL KHVNQCVKVH AEIRDPEMRS WSGVTYPDNK
     LVIGVADGTT PAGKTHCVFF GCDANHMHAD EDIDQTLQAI QEFAPMEIDR LVFHNWSKDE
     FAKGAWVWYR PGMEVQYLEA LRKRQGPVLF ANSDWAAGGW RSFIDGAIQS GTEAALTVRQ
     ELMPILRTSR L
//