ID W9X5U8_9EURO Unreviewed; 854 AA.
AC W9X5U8;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Elongation factor 2 {ECO:0000256|ARBA:ARBA00017891};
GN ORFNames=A1O5_03857 {ECO:0000313|EMBL:EXJ72710.1};
OS Cladophialophora psammophila CBS 110553.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC Cladophialophora.
OX NCBI_TaxID=1182543 {ECO:0000313|EMBL:EXJ72710.1, ECO:0000313|Proteomes:UP000019471};
RN [1] {ECO:0000313|EMBL:EXJ72710.1, ECO:0000313|Proteomes:UP000019471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110553 {ECO:0000313|EMBL:EXJ72710.1,
RC ECO:0000313|Proteomes:UP000019471};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Cladophialophora psammophila CBS 110553.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ72710.1}.
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DR EMBL; AMGX01000005; EXJ72710.1; -; Genomic_DNA.
DR RefSeq; XP_007742657.1; XM_007744467.1.
DR AlphaFoldDB; W9X5U8; -.
DR STRING; 1182543.W9X5U8; -.
DR GeneID; 19188584; -.
DR eggNOG; KOG0469; Eukaryota.
DR HOGENOM; CLU_002794_11_2_1; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000019471; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR CDD; cd03700; EF2_snRNP_like_II; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF10; ELONGATION FACTOR 2; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EXJ72710.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000019471}.
FT DOMAIN 17..346
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 854 AA; 94580 MW; AA64A17AC0638E17 CRC64;
MVNFTIEEIR ALMDKPANIR NMSVIAHVDH GKSTLTDSLV QRAGIISAAK AGEARFTDTR
KDEQERGITI KSTAISLYAH LPNEEDLKDI PQKVDGNEFL INLIDSPGHV DFSSEVTAAL
RVTDGALVVV DTIEGVCVQT ETVLRQALGE RIKPVVIINK VDRALLELQL QKEDLYQSFL
RTIESVNVII STYLDKALGD VQVFPEKGTV AFGSGLHGWA FTVRQFAVRY AKKFGVDKNK
MMERLWGDNY FNPKTKKWTK TAEHEGKNLE RAFNQFILDP IFKIFDAFTK GKVDQLVELC
AKLDIKITSE EKELPGKGLL KAAMRKFLPA ADALLEMMVI HLPSPVTAQK YRAETLYEGP
ADDPACIAIR DCDPHADLML YVSKMVPTSD KGRFYAFGRV FAGTVRSGMK VRIQGPNYVP
GKKEDLFVKS IQRTVLMMGR TVEPIDDMPA GNIIGLVGID QFLLKSGTLT TSETAHNLKV
MKFSVSPVVR RSVEVKNAND LPKLVEGLKR LSKSDPCVLT QISESGEHIV AGAGELHLEI
CLKDLEEDHA GVPLKISDPV VSYRETVGGT SSMTALSKSP NKHNRLYVIA EPLGEEVSKD
IENGKITPRD DFKARARILA DEHGWDVTDA RKIWAFGPDT TGANLLVDQT KAVQYLNEIK
DSFVSGFQWA TREGPIAEEA MRSIRFNIMD VTLHADAIHR GGGQIIPTAR RVLYAATLLA
EPGLLEPVYL VEIQVPEQAM GGIYGVLTRR RGHVFSEEQR VGTPLFTVKA YLPVLESFGF
NADLRAATGG QAFPQSVFDH WQILPGGSPL DSTTMVGKVV MEMRKRKGLK EQVPSYDNYY
GEFPFALSGI LDNC
//
