ID W9Y445_9EURO Unreviewed; 1083 AA.
AC W9Y445;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Replication factor C subunit 1 {ECO:0000256|ARBA:ARBA00020401, ECO:0000256|PIRNR:PIRNR036578};
GN ORFNames=A1O3_10397 {ECO:0000313|EMBL:EXJ77239.1};
OS Capronia epimyces CBS 606.96.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Capronia.
OX NCBI_TaxID=1182542 {ECO:0000313|EMBL:EXJ77239.1, ECO:0000313|Proteomes:UP000019478};
RN [1] {ECO:0000313|EMBL:EXJ77239.1, ECO:0000313|Proteomes:UP000019478}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 606.96 {ECO:0000313|EMBL:EXJ77239.1,
RC ECO:0000313|Proteomes:UP000019478};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capronia epimyces CBS 606.96.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036578}.
CC -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC {ECO:0000256|ARBA:ARBA00006116, ECO:0000256|PIRNR:PIRNR036578}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ77239.1}.
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DR EMBL; AMGY01000011; EXJ77239.1; -; Genomic_DNA.
DR RefSeq; XP_007738677.1; XM_007740487.1.
DR AlphaFoldDB; W9Y445; -.
DR STRING; 1182542.W9Y445; -.
DR GeneID; 19174477; -.
DR eggNOG; KOG1968; Eukaryota.
DR HOGENOM; CLU_003574_1_1_1; -.
DR OrthoDB; 6297at2759; -.
DR Proteomes; UP000019478; Unassembled WGS sequence.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006271; P:DNA strand elongation involved in DNA replication; IEA:UniProt.
DR CDD; cd00009; AAA; 1.
DR CDD; cd17752; BRCT_RFC1; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012178; RFC1.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF6; REPLICATION FACTOR C SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08519; RFC1; 1.
DR PIRSF; PIRSF036578; RFC1; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR036578};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR036578};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR036578}; Nucleus {ECO:0000256|PIRNR:PIRNR036578};
KW Reference proteome {ECO:0000313|Proteomes:UP000019478}.
FT DOMAIN 334..413
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 984..1083
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..79
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..175
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..242
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..287
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..457
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 997..1015
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1016..1031
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1042..1066
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1083 AA; 118149 MW; D93E7E8D734A9E5B CRC64;
MPDIRSFFGG GGGGAKAAAK GVGSEATKKN ISTSKQNSKQ RGRARKVVSD DEDDDEVVET
KPKKSSTPKA KRIVKEPVEE EITSSAYFAS SKASRSKSTP IKTKAANANG TANSPSKTTN
AETPSSGRRS TRKTTMKNYT EDDAEIPNTV LQDDSEGHDD IFNDFKSRKV DDDYEEGSDA
DVLMPQKKNN KAANGNAKKP LPDEDDDDVE VAEIPIYDRP GDRKKRSAAP SNRKRKSKDL
DEDEDNDFLD DGDATPKKKP RKTTATTSTR PRAPAKKEER EESKEIQDIL SSIPTVRAPT
PPPRDENKKF TFQPGGGNAS VAPPAAGTAE IPVGAENCLT GLTFVFTGVL NALGREEGQN
LVKQYGGKVT GAPSKKTSYV VIGSDAGPKK LETIQKLGIK TINEEGLFEL IKRLPANGGD
GKAAEAYAEK QAKEDAKIRK EAEEMERREK ERQQEAAKVA KAAAARTGAS VPADKSQGRK
VDDRLWVDKY APDSLSSVCG NKSAVEGLQR WLRNWPNNAK SNFKKAGADG KGIFRAALLH
GPPGVGKTTA AHLVAKLEGY DIVESNASET RNKKLLEQGL TGVLDTTSLL GYFAGDGKKV
DPSKKKIVLI MDEVDGMSAG DRGGVGALAA VAKKTHIPMI LICNERNLPK MKPFYHVTAE
FQFRRPTTDM IRGRIATILF REGMKLPPPI MNALIEGCNG DIRQIVNMIS TIKLDNKDLE
FSDTKAMSKA WEKHVILKPW DIVSKILRPQ MFAPSSTATL NDKTELYFND HEFSYLMLQE
NYLKTQPSLA ASYHGKERDM KMLELIDNAA SSISDGDLVD RMIHGSQQQW SLMPVHAIFS
FVQPASFVYG NLNGQVSFAG WLGQNSKQGK LSRFIKEIQG HMRLRANADR NEVRQQYLPA
LWDKTVGTLQ NEGKEAVQDV IDFMDSYYLT KDDFDAMLEL GVGPMDQEKV KLETATKATF
TRLYNSQSHP MPFVKASNVL GVAKGAGPKE KPDLEEAVDE SEPDEVLDVE AEEAEDEALD
LKKDKYIKAP KKKSTAAGGA KGKGKRKKDG EDADGDDSEE PPKKKRASGG GGGGGGRKGK
GRA
//
