ID X0A2W0_FUSOX Unreviewed; 834 AA.
AC X0A2W0;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Transcription factor BYE1 {ECO:0000256|ARBA:ARBA00021616};
GN ORFNames=FOMG_10392 {ECO:0000313|EMBL:EXK35182.1};
OS Fusarium oxysporum f. sp. melonis 26406.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089452 {ECO:0000313|EMBL:EXK35182.1};
RN [1] {ECO:0000313|EMBL:EXK35182.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=26406 {ECO:0000313|EMBL:EXK35182.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum melonis.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EXK35182.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=26406 {ECO:0000313|EMBL:EXK35182.1};
RG The Broad Institute Genomics Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "Annotation of the Genome Sequence of Fusarium oxysporum f. sp. melonis
RT 26406.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Negative regulator of transcription elongation.
CC {ECO:0000256|ARBA:ARBA00002311}.
CC -!- SIMILARITY: Belongs to the BYE1 family.
CC {ECO:0000256|ARBA:ARBA00011050}.
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DR EMBL; JH659335; EXK35182.1; -; Genomic_DNA.
DR AlphaFoldDB; X0A2W0; -.
DR VEuPathDB; FungiDB:FOMG_10392; -.
DR HOGENOM; CLU_009292_0_0_1; -.
DR Proteomes; UP000030703; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd21538; SPOC_TFIIS; 1.
DR Gene3D; 1.10.472.30; Transcription elongation factor S-II, central domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR012921; SPOC_C.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11477:SF20; PROTEIN PARTNER OF SNF, ISOFORM B; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF20826; PHD_5; 1.
DR Pfam; PF07744; SPOC; 1.
DR Pfam; PF07500; TFIIS_M; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00510; TFS2M; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 241..369
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 124..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 669..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..65
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..150
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..384
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..437
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..720
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 721..744
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 834 AA; 91784 MW; CF2E7ACC923AF052 CRC64;
MSGEAEPRRS VRATKGQHTK SFDELEPATV PKKRQTKKTK KAKEQEQEQE QEQQQEQEEE
EEDELIRCVC GATEQDEDSG EAWIACETCG AWQHNVCVGV SSFDDEIPEH YWCEQCRPDD
HKELLDGIAK GEKPWEARRK AHEEESKKKK RGGRKGKGKR HSETKEEDKT KAKSSPVPVP
DATKDKKETK TGKRKAREES HDADGKSAKV RRISENGATP VPVSYTPPDD LAKSISDLPG
SRTGPAKAMS KSISHVLTSM QKQGELDLEE GNTIESMTET FSLQIERAVY DSYPVTKGQK
EYNQQIKSLS FNLKNNPELC HGLVHKTLSP AALATMTSEQ LASSEMKKQT AEMKAKAEKQ
SILYTSETGP RVRRTHKGEE VVDDETFVND SAVPLPPGPP RRPEPQAVKK EPTGGDKADL
ASHPQQQDDK QRSPSHPDFD INEVFSSVKS PTTTQNRRPS ALVTGSNGPG VDPDVDRMLQ
DENESPPYSP TEETQDPDVI WQGSLAMSSI ADFPATAKYI GGANFASVGP WSKLIPKRMM
VAGRIPEQSA IEYLCSLRYS NSTDVIVVSV SPVSPFSHTE FHNLLNYFTS KKRYGVIGDK
TIGNVRDTYL VPVPAGEDNY PEFMLNLVDN KIPKVRTEPI LLAVFVYHNE PDQLKHLKDG
TANQQDAKAL GTPVPAAHAQ RSNSTASAGP AFSPATPQAP QGGFQGGFPQ QSSPGQWQST
TPVPIPQPPY TRPPVPPQAP TPAPAAAPAQ MLEAQRHQAQ QAGVAMAHEL LGPWITSPTV
QFILPQAYQM ARKEWEVVRR VLERDPKARD DLQHLGNLLE KETAADKTGG AAAA
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