ID X0AHP7_FUSOX Unreviewed; 517 AA.
AC X0AHP7;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=PLD phosphodiesterase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=FOMG_07282 {ECO:0000313|EMBL:EXK40387.1};
OS Fusarium oxysporum f. sp. melonis 26406.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089452 {ECO:0000313|EMBL:EXK40387.1};
RN [1] {ECO:0000313|EMBL:EXK40387.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=26406 {ECO:0000313|EMBL:EXK40387.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum melonis.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EXK40387.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=26406 {ECO:0000313|EMBL:EXK40387.1};
RG The Broad Institute Genomics Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "Annotation of the Genome Sequence of Fusarium oxysporum f. sp. melonis
RT 26406.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH659332; EXK40387.1; -; Genomic_DNA.
DR AlphaFoldDB; X0AHP7; -.
DR VEuPathDB; FungiDB:FOMG_07282; -.
DR HOGENOM; CLU_007773_2_0_1; -.
DR Proteomes; UP000030703; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd09122; PLDc_Tdp1_1; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR010347; Tdp1.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12415; TYROSYL-DNA PHOSPHODIESTERASE 1; 1.
DR PANTHER; PTHR12415:SF4; TYROSYL-DNA PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF06087; Tyr-DNA_phospho; 1.
DR Pfam; PF02809; UIM; 1.
DR SMART; SM00726; UIM; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50330; UIM; 1.
PE 4: Predicted;
FT REGION 26..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..97
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 479..493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 220
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-1"
FT ACT_SITE 458
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-1"
FT BINDING 222
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-2"
FT BINDING 460
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-2"
FT SITE 513
FT /note="Interaction with DNA"
FT /evidence="ECO:0000256|PIRSR:PIRSR610347-3"
SQ SEQUENCE 517 AA; 57119 MW; 88ADD583A5AC7E17 CRC64;
MAGSREDPVE LGSDMDEDEA LRYAIALSLQ EQEEQGDQSS QIPSASTSTS HRKGTGSGGA
SLGLLSLDRK KMEEERLQRL AKRRRSPEDE RSVDEVPPAK RMTPSEPSRT VTATATAHVL
PSFVPYPKGA IKRTWAKGYP RTSDDIKIEE VFQKDKLELA LLSSYQWDDE WLMSKIDPRK
TKLLLLAFAD SEAQKSEMRS NAPPGIKFVF PAMNGPGAMH SKLQLLKYPD YLRVVVPTAN
LVPYDWGETG VMENMVFLID FPRLKDPATY RQTAFSTELG RFLSATGVGE GMVSSLANYD
FSQTKHLGFV YTIPGGHQGD SLKRIGYSGL GTTVAALGLA TDEPIEVDFV CASLGSLNYD
LVGAIYNACQ GDDGMAEYKS RIGRTGAASK NKASNPWQEK LKDRFRIYFP TEETVGRSRG
GRNAAGTICV QPKWWRSPTF PTELVRDCVN TRDGLLMHSK MIMVSQMQAG SQLQTRPQTR
PEPRHHDSGP AAAEPKTEEM SLGWVYIGSA NLSESAW
//
