ID X0AXK6_FUSOX Unreviewed; 1241 AA.
AC X0AXK6;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Clustered mitochondria protein homolog {ECO:0000256|HAMAP-Rule:MF_03013};
DE AltName: Full=Protein TIF31 homolog {ECO:0000256|HAMAP-Rule:MF_03013};
GN Name=CLU1 {ECO:0000256|HAMAP-Rule:MF_03013};
GN Synonyms=TIF31 {ECO:0000256|HAMAP-Rule:MF_03013};
GN ORFNames=FOMG_08362 {ECO:0000313|EMBL:EXK37761.1};
OS Fusarium oxysporum f. sp. melonis 26406.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089452 {ECO:0000313|EMBL:EXK37761.1};
RN [1] {ECO:0000313|EMBL:EXK37761.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=26406 {ECO:0000313|EMBL:EXK37761.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum melonis.";
RL Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EXK37761.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=26406 {ECO:0000313|EMBL:EXK37761.1};
RG The Broad Institute Genomics Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "Annotation of the Genome Sequence of Fusarium oxysporum f. sp. melonis
RT 26406.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: mRNA-binding protein involved in proper cytoplasmic
CC distribution of mitochondria. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBUNIT: May associate with the eukaryotic translation initiation
CC factor 3 (eIF-3) complex. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SIMILARITY: Belongs to the CLU family. {ECO:0000256|HAMAP-
CC Rule:MF_03013}.
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DR EMBL; JH659333; EXK37761.1; -; Genomic_DNA.
DR AlphaFoldDB; X0AXK6; -.
DR VEuPathDB; FungiDB:FOMG_08362; -.
DR HOGENOM; CLU_003256_2_0_1; -.
DR Proteomes; UP000030703; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007005; P:mitochondrion organization; IEA:UniProtKB-UniRule.
DR GO; GO:0051640; P:organelle localization; IEA:UniProt.
DR CDD; cd15466; CLU-central; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR HAMAP; MF_03013; CLU; 1.
DR InterPro; IPR033646; CLU-central.
DR InterPro; IPR025697; CLU_dom.
DR InterPro; IPR028275; CLU_N.
DR InterPro; IPR027523; CLU_prot.
DR InterPro; IPR023231; GSKIP_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12601:SF6; CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG; 1.
DR PANTHER; PTHR12601; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3; 1.
DR Pfam; PF13236; CLU; 1.
DR Pfam; PF15044; CLU_N; 1.
DR Pfam; PF12807; eIF3_p135; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 2.
DR SUPFAM; SSF103107; Hypothetical protein c14orf129, hspc210; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51823; CLU; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_03013};
KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_03013};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 300..544
FT /note="Clu"
FT /evidence="ECO:0000259|PROSITE:PS51823"
FT REPEAT 977..1010
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 587..662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 867..907
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1183..1241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 587..636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1183..1204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1209..1226
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1241 AA; 137564 MW; 7705A7269A7F33E3 CRC64;
MEAEAQDVDA GAEALINLTI VLPDANASKM QIMVSSQEQV HEIRQSIIDL PSAFQYTCFH
LEFNGEKIND FIPLSEIPDL GTTPEFHVVE DPYTEKEARI HFVRIRELIG ASGDRCDTAQ
GLLPGLSLFE TVATEAVSNN ESAEESPIQN YDFQAVPSLT ELVPPPSEPA PKTVKQISLS
SWNPPPPHLR QRGHLLYLVV STNEGEQYQI TSHVSGFFVN KSSNAKFDPF PRPAPKGQSA
HSLLSLIELV SASFAESFTK LQDYNNQRDP LATFQITNAI PAAPWVVPSP NSTLCTHLPD
PARSQETYLL NGVENTDTLR DWNEEFQSAK ELPRETVQDR VFRERLISKL FADYNEAATR
GAVMVARGDI APLNPTECRD AQIFVYNNIF FSFGADGVGT FTSEGGDEAA RVATGKDVAG
VKLVNQLDIE GLFTPATVVV DYLGKRIVGQ SIVPGIFKQR EPGENQIDYG AVDGKDIVAA
DERFAPGFAQ LSKALKVKKH PVWDKEGKRF DLEASVETKG LLGTDARKYV LDLYRISPLD
IAWLDEDGLP EDGDAYPHRM TVLRPELVDS FSRYKLKQWV DKEVARRAEQ KKEKEGETKA
AEGDAKGEED ESEKKTTEGE GEGEGEASKE EDNQPNLSDF KFALNPDAFS GQVPQTDEEK
AEFAADEEEV RAAGKYLREQ VIPDLLKDLS ESEISFPMDG QSLSRLLHKR GINVRYLGKV
AELSSDGRLR CLRDICVQDM VARAFKHVSA VYLRHLPVPA VPATVSHLLN CLLGHRFNEK
PVAELDPSIR SLYTDADWSF EKVTPESLRE NIEEQILQRF RYELDEEWHN QVRPVQLLRE
VSLKIGIQLL AKDYSFTAEA AATASEAAPA KVEKPVANGQ NNGESVSSKK KKKSKAREAS
PVEAAAPANV HTFSPEDVID LVPLIKDSCP RSALAEEALE AGRISLLQNQ KKLGQELLLE
SLSLHEQIYG ILHPEVARVY NSLSMLYYQL DEKEAAVDLA RKAIIVAERT VGVDSAETLL
NYLNLSLFLH QIGDSKGALV YSKHALKMWK VIYGPDHPDS ITTLNNAAVM LQNLKAYHES
RLWFEESLRV CESVFGKQSI NSATLLFQLA QALALDRDSK GAVTRMRESY NVFLAELGPE
DKNTKEAESW LEQLTQNAVN IAKHAKDVAA RRLRTGVRFT TSPSSLAASN ATVPGRTGPG
SQVDSRSIDE LIKFIEGGEH QQTKKRTGRG NPKRRGQAGA R
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