ID   X0GYJ0_FUSOX            Unreviewed;       816 AA.
AC   X0GYJ0;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Phosphoketolase {ECO:0000313|EMBL:EXL64965.1};
GN   ORFNames=FOPG_18791 {ECO:0000313|EMBL:EXL64965.1};
OS   Fusarium oxysporum f. sp. conglutinans race 2 54008.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=1089457 {ECO:0000313|EMBL:EXL64965.1};
RN   [1] {ECO:0000313|EMBL:EXL64965.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=54008 {ECO:0000313|EMBL:EXL64965.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA   Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA   Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA   Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Fusarium oxysporum PHW808.";
RL   Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EXL64965.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=54008 {ECO:0000313|EMBL:EXL64965.1};
RG   The Broad Institute Genomics Platform;
RA   Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA   Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Annotation of Fusarium oxysporum PHW808.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000256|ARBA:ARBA00005623}.
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DR   EMBL; KK033811; EXL64965.1; -; Genomic_DNA.
DR   AlphaFoldDB; X0GYJ0; -.
DR   HOGENOM; CLU_013954_2_0_1; -.
DR   Proteomes; UP000030676; Unassembled WGS sequence.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd02011; TPP_PK; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PHOSPHOKETOLASE-RELATED; 1.
DR   PANTHER; PTHR31273:SF0; PHOSPHOKETOLASE-RELATED; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052}.
FT   DOMAIN          22..383
FT                   /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT                   phosphoketolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09364"
FT   DOMAIN          601..802
FT                   /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT                   phosphoketolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09363"
SQ   SEQUENCE   816 AA;  91401 MW;  66AEB7031C189A57 CRC64;
     MAKVESIRSF GLARSTIKGS PLSKEEIEQS NDYFKASCYL SLGMIYLKEN PLLREPLKPE
     HLKLRLLGHF GSAPGQVFTY MHFNRLIKKY DLDSIFISGP GHGAPAVLSQ SYLEGVYSEV
     FPDKTLDAEG LQKFFKSFSF PGGIGSHATP ETPGSLHEGG ELGYSISHAF GTVYDNPDLI
     ALTMVGDGEA ETGPLATAWH SNKFLNPIVD GAVLPVLHLN GYKINNPTIL ARISHKELEN
     LFLGYGWQPY FVEGDDVETM HQAMAATLEH CVTEIRKFQK QARESGEAFR PIWPMIVLRS
     PKGWTAPRKV DDNYLAGFWR AHQVPITDPA TNSAHLKLLE EWMRSYEPDR LFDESGAPLA
     SLRALTPSGN RRMSANPVAN GGLLRKPLRM PDFRDYAIKV DSPGNVVSAS MTNMAVFLKD
     VIAENQNNFR LFGPDETESN KLGGVYAAGK KVWMGEYFEE DENGGNLAKS GRVMEMLSEH
     TCEGWLEGYI LSGRHGLLNS YEAFIHVIDS MVNQHCKWIE KCLEVEWRAK VASLNILLTA
     VVWRQDHNGF THQDPGFLDV VANKSPEVVR IYLPPDGNCL LSVMDHCLRS VNYVNVVVSD
     KQEHLQYLSM DAAIEHCTKG IGIWPQFSTD AGQDPDLIMA SCGDISTYES LAAIDLLLEH
     FPELKIRCVN VVDLFKLIHP SDHSHGLSDV EWTSVFTDDT PIIFNFHSYP WMVHRLTYKR
     PGSRNLHVRG YKEQGNINTP LELAIRNQTD RFSLAIDAID RMPQLHNRGA SARQALLNAQ
     IQARNEAFAT GVDPPFLKDW TWKRNGLASR QSGLEQ
//