ID X0ILF3_FUSOX Unreviewed; 1063 AA.
AC X0ILF3;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=phosphatidylserine decarboxylase {ECO:0000256|ARBA:ARBA00012243};
DE EC=4.1.1.65 {ECO:0000256|ARBA:ARBA00012243};
GN ORFNames=FOPG_03239 {ECO:0000313|EMBL:EXL84770.1};
OS Fusarium oxysporum f. sp. conglutinans race 2 54008.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089457 {ECO:0000313|EMBL:EXL84770.1};
RN [1] {ECO:0000313|EMBL:EXL84770.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=54008 {ECO:0000313|EMBL:EXL84770.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum PHW808.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EXL84770.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=54008 {ECO:0000313|EMBL:EXL84770.1};
RG The Broad Institute Genomics Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Annotation of Fusarium oxysporum PHW808.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyruvate; Xref=ChEBI:CHEBI:15361;
CC Evidence={ECO:0000256|ARBA:ARBA00001928};
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis. {ECO:0000256|ARBA:ARBA00024326}.
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DR EMBL; JH658811; EXL84770.1; -; Genomic_DNA.
DR AlphaFoldDB; X0ILF3; -.
DR UniPathway; UPA00558; -.
DR Proteomes; UP000030676; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004609; F:phosphatidylserine decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd04024; C2A_Synaptotagmin-like; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR003817; PS_Dcarbxylase.
DR InterPro; IPR033177; PSD-B.
DR NCBIfam; TIGR00163; PS_decarb; 1.
DR PANTHER; PTHR10067; PHOSPHATIDYLSERINE DECARBOXYLASE; 1.
DR PANTHER; PTHR10067:SF17; PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME 2; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF02666; PS_Dcarbxylase; 1.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Pyruvate {ECO:0000256|ARBA:ARBA00023317};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT DOMAIN 42..161
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 279..400
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 530..565
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 424..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 631..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..260
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..458
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..688
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1063 AA; 118906 MW; A2DC694F10EDA2BB CRC64;
MVRIIPTRLK STSRSSSSSS TTIHSVSNTN GRTKNNRSNS PPMRSKNDST SPSRDAGNGL
ALRVYIIKGK DLAAKDRSGT SDPYLVLSSG DSRIVTNDVP KTLNPEWNVT EEIPLTSVQN
LVLDVICWDK DRFGKDYMGE FDLALEEIFN NDKVEQEPTW YRLKSKRPGK KTSVVSGEVQ
LQFSLFDSTN PSATPQQILE KFQALVGTAP AGSRNVTPSM TPNLAPTGSQ SAPNPQDSPS
DDDEDDFDED DSDEGDEDEG EQDATKRKRR LRIRGLKKRR RNNPYAFASS GSDVVGIIYL
EVIKITDLPP ESNLTRTSFD MDPFVVASLG KKTYRTRRIR HDLNPVYNEK MLFHIQSHEQ
QYSFAFTVID HDKYSGNDFI ASCDLPIHQL IERAPKANPE TGLYDLQAPA QAEPLPSRSR
FKKLAMSRSN SSSSISKMIR PPLSKHASNT SMASATPAPA PTSAPDPNKL APADVLANTG
SDPDSANQDS GDADFYEYNV PLKMKNTEKW EKKHNPVLYL RAKYMPYDAL RQQFWRAMLR
QYDADESGRI SRIELTTMLE SLGSTLTENT IDGFFKRFPH RDADNDENWE LTMDECVICL
EDQLEGRRRS SGTAADKLKG LVPEMKNLLH VPGHGHNNGG SETPSVLELD STSGTQTPIS
NVPTLKTPAD EEGDPLDKSD SSDDRSEEHV VEIRECPICH QPRLNKRKDA DIITHIATCA
SQDWRQVNSV LVGGFVTASQ AQRKWYSKVI TKISYGGYKL GANSANILVQ DRLTGQINEE
KMSVYVRLGI RLLYKGLKSR DMENKRIRKL LKNLSIKQGK KFDDPASKDE IEKFIAFHGL
DMSEVLLPLD EFNNFNEFFY RALKPGARPC SAPDNPHIIV SPADCRSVVF NSITVATKIW
VKGREFNMKR LLGDAYPEDV SRFEGGALGI FRLAPQDYHR FHIPVDGVMG KPKTIEGEYY
TVNPMAIRSA LDVYGENVRV LVPIDSEHHG RVMVICVGAM MVGSTVITRK EGDRVHRAEE
LGYFKFGGST ILLLFEPGRM VFDDDLVDNS KDALETLVSN LHW
//
