ID X0LPI1_FUSOX Unreviewed; 1233 AA.
AC X0LPI1;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Sorting nexin-12 {ECO:0008006|Google:ProtNLM};
GN ORFNames=FOTG_09439 {ECO:0000313|EMBL:EXM23117.1};
OS Fusarium oxysporum f. sp. vasinfectum 25433.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089449 {ECO:0000313|EMBL:EXM23117.1};
RN [1] {ECO:0000313|EMBL:EXM23117.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=25433 {ECO:0000313|EMBL:EXM23117.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum Cotton.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EXM23117.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=25433 {ECO:0000313|EMBL:EXM23117.1};
RG The Broad Institute Genomics Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Annotation of Fusarium oxysporum Cotton.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; KK035210; EXM23117.1; -; Genomic_DNA.
DR AlphaFoldDB; X0LPI1; -.
DR HOGENOM; CLU_002131_1_0_1; -.
DR Proteomes; UP000030701; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06876; PX_MDM1p; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 98..287
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 414..552
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 882..1000
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 302..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..801
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 839..873
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 564..589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..629
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 787..801
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1233 AA; 137980 MW; 7DCAF091ED0DCE5D CRC64;
MALKRRDVIV AGLAAFIAWG FAASWSPVLR WAGHAFVAGS VVTLVALLAG LFLVSRRPSD
RILQPHGVTF LGKKSWRLEV QGLRQRQSYT PTPIDPESPR VSEAIDNLLG LITRDFVNSW
YSNISRNPCF SNQVDQAVRQ ALLSLTDFLR HKDLAELVTS RLVPLLTAHF RDFYEAEKSV
RGKKLNRSVT ESEELDLAIA SKFRDGRLHP AASLSFPDTK MVQQDYLRSL VAKIVPQILP
ENMLSSRAVS IIIREIVACA VLFPVIQLLS EPDTWNQLME NLGRSMLQDR STVRKLRAAL
DQHAPSTPKA NKLASMPRVA PGDSERKFEK FIRAIRKVNN LSDARRFRSE VASQLKRDSL
EDNQDQVYLR RLEMGKRLLD QRVNHLAAGG ERRPPGPLPL PSTSSSQSKL ESAPLVDILR
DSSALSYFME YMDRQNLMPL VQFWLVVDGF RNPLEDDGPD DELPSTLPMW TDADRQDLQQ
INQAYLSRPE LKVPDHSRNE VKEFIKAGKS ATPLQYYRAR RAILKAQSAV LEEMRSRFFQ
SFKKSDLFYK CLAAEEAANI QTLRSTPQPE VQAQAQTQTQ ASATNRASKT LPAKPRPVSR
LTPQLSNAGK RTGSASDLKS LTSNGNGHGH RARRSLDEGS FNPLFDDDDI DTDGLGDSVQ
SLDPDANSQQ LPDTQVVKAV EQAFTDIMED DRPQTAEALR ASLFGGPGGS SIGGIDDNAS
SLFSGNDNES HRGSLDMGIR PAMANKEGEK PSLSSLGLVS AASRIGVFVD DDLFGDNNKD
LPDDGDPDDG PPPDDEDEVH EAAPGDLGLA EAITALSNDI DRLVAQEAVV ESLTRKAELT
NNTAELRILR KSKASLQREI RRKELQRQQY VIQESDNSLY GRSTIKIKSI QVGREEDGRE
FALYVIEVQR NAGEQMPAAS WVISRRYSEF HELHQKLRSR YPSVRNLDFP RRRMVMKFQS
EFLRKRRTAL QQYLQDLLLL PEVCRSRELR AFLSQSVITQ GQDILDREDK KDMMTRLYDS
VADGMDDILG NIPVLDQISE AGQNLIAAAT NQLNAVPLNI NEDTFPAAEA EAELNAFENK
ELEPFIKPIC DIFLEIFELN KGNNWLRGRA VVVVLQQLLG GTIERKVRDN VKMLVQDENI
LKYIALVQDS LWPGGQLQRD RKPRTAAEKK KTRTEASLML ATLVPDLAGS VVGRVNAQTA
SRRIFATLNN SRLNAHLVFT MIDEIVSVLF EEP
//
