ID X0LT41_FUSOX Unreviewed; 1964 AA.
AC X0LT41;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN ORFNames=FOTG_08766 {ECO:0000313|EMBL:EXM24342.1};
OS Fusarium oxysporum f. sp. vasinfectum 25433.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089449 {ECO:0000313|EMBL:EXM24342.1};
RN [1] {ECO:0000313|EMBL:EXM24342.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=25433 {ECO:0000313|EMBL:EXM24342.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum Cotton.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EXM24342.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=25433 {ECO:0000313|EMBL:EXM24342.1};
RG The Broad Institute Genomics Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Annotation of Fusarium oxysporum Cotton.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH657937; EXM24342.1; -; Genomic_DNA.
DR Proteomes; UP000030701; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd07589; BAR_DNMBP; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR22834; NUCLEAR FUSION PROTEIN FUS2; 1.
DR PANTHER; PTHR22834:SF20; NUCLEAR FUSION PROTEIN FUS2; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1253..1470
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 20..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 77..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 765..879
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 923..1081
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1093..1131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1152..1173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1744..1811
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1828..1927
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..57
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..333
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..423
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..609
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 641..661
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..853
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..999
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1000..1062
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1109..1127
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1757..1774
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1775..1810
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1828..1895
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1964 AA; 216815 MW; 94136990786B32E9 CRC64;
MDNDMDMALH AGLQADVQDV DSGFRNPNLE PHHDLHHLSQ HNKNQRPYDH DNDHNRRIDH
TTDLRQDYLN DQLSHDRRHY LPDSSPSAAP ASHFDQRSTY SHPSVPHADE YDSISTGAHH
AFAPVNPDDF YKSYRGTYHN NQESLFIGAS ALRPSLRSNG DGSTPKHHIT SQTEINMRST
SNPVDNRPAL PGYKPTGTHP SVRDLKRRFD QNGAAPSSIP RAPAHTGAAA KIRQDVGVSP
QPRNGATSYS TLRDGSNSFS NQTVSSSARS QRSRYVAEDQ VSNNSQSFAS RIGKPRSTTS
GNSNASKPTS NLAPESPPQQ PTSSISPTPS RSQGLLFGEI LPEQHSFPTA GYGIEGVRPR
RTSESSLHHP FSHQRSLSDP PDVAEPSSPS IWYRSLNGDD NNGQPTQAPQ KGHTRSHSDI
PKSPSVPPVS RKTPSRKPPT TNTSGAGSTS KLPRSVRKVN SPSDSTPSTR SNSPTLKRPQ
VNGRTSRAGT PTTRAKTPTR AKTPTQSGAT RKTAPRTLVT PTNNNRLQAN IIAPPPKLSP
PLRSSRPRQP VSVATTASSR MRAVERARSP NPTSIPQSRI AEPSSRRRKI SVGPIDFEQR
REHIRLAYTK SIRESQALEA RQKAADRRRR EMEAAARAKA TAAASSNSNS PSVTPEPSIT
ESPTLADIPP VPPLPDDHLV SSDFRIGSGP SLSPEVSNAT EVQNTLNVVD LSDTLAFPGS
HEVSYDQPDG EPPRDQPSPF LDDPTMSPVD IAMALPPASL MLAATSQATL TDEPSAQDFD
SPTLGVPGSF PALSPSPVGE SERPPTAVSV TSETTEFDNE PQMTPPRSSQ TPLEVPITII
KPPSPQTQKS ASPLKAEYHY PFEDDPDSPV RPKSASNTVD VAEHALSKHD EVTLPFIPGA
FDIEAKADEP NPGVESYKTT ITILPPSDEP RAAESLEETV PFPRIEPDYE SECHSDSEYD
EVARQYRRSH DDGAITDSCT EDVEEAGRND CRSEVPSDDQ VSSHRASTCE SLDTNNEPHY
ASDEQQRPEI STNLMVPTLS ATNRTSQQSA WTDFSINSGD MSPAGRSPVF PDDDENETGD
HGHVTIFETT SIHRNSRPVE RPLEIRNSQP EIRPSTDLTQ SPYLSHQLPE LDTGDGFSIP
YLSNRASKSF SYFPSPNHEP PPIPASASGS ACNSQRASGV YYEQSQSGST FVNSERGSQD
YIPMMTTPQS MDNTSLSTHN QYFADATTLN GDANSETYDK QGPTGKEKQR LVQRRNVIKE
LVDTEAVFVR DMNIVEEIYK GTAEACPKLD GNTVKLIFRN TDEIITFHTS FFAQIKEAVL
AVYTMQSRRS ALAREGTLIS EPSQFNPADI DDTKDRSVLI GPVFKANMEK MKLAHEGFLR
NSDGAAKRLI QIQQDPTVKV WLNECNEVAK DLTAAWDLDS LLIKPMQRIT KYPNLIITLL
QHTPQDHPDR EGLIEAKEIL ETAIIEINKT KKNFELVGQI VGRKRKESDV KAGFARAFGK
RVDKLQASGT RTSEDSEYAK LNEKFGDDYL RLQVVLRDVE FYTRQVSAYV HEFLQYLSSI
ELVMRLQPGN HPELESKWVQ FNISMRDLEK VALEEHLSQV RKHVIEPFEH VIKAYGNPSL
AMKKRQKRRV DYERYEQLKR AGKSIDSKLN ELVEQYDALN DTLKKELPKL SALTEKVGNI
CLGNFVNIQT RWYGIWKDKM KLVLGDCPDM PDLKEVVATF QRDFPYQQEQ LASIGILNPM
YRGRVSQSTT RSTEESSSLR MRSRPSESDS RGRGHSISGE QTQSVPTPEF TKRHSGSYTA
SPTGVTAGNI PSPHQYYYRD YYSGIGNHQQ GTASPLSPDL PGSTRSFAAS TRPSTGRSFD
SGGLPRQSSD SATQQLRDSH TTYSSQNQSQ EGRRFSGLFH SALPPADGPE DSARSSRASS
RERGPTDDGY NVLWLAASLF EFNIATTKHE AGYPYLVYQA GEVS
//
