ID X0MA03_FUSOX Unreviewed; 1097 AA.
AC X0MA03;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=alpha-glucosidase {ECO:0000256|ARBA:ARBA00012741};
DE EC=3.2.1.20 {ECO:0000256|ARBA:ARBA00012741};
DE AltName: Full=Glucosidase II subunit alpha {ECO:0000256|ARBA:ARBA00042895};
GN ORFNames=FOTG_14311 {ECO:0000313|EMBL:EXM17470.1};
OS Fusarium oxysporum f. sp. vasinfectum 25433.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089449 {ECO:0000313|EMBL:EXM17470.1};
RN [1] {ECO:0000313|EMBL:EXM17470.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=25433 {ECO:0000313|EMBL:EXM17470.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum Cotton.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EXM17470.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=25433 {ECO:0000313|EMBL:EXM17470.1};
RG The Broad Institute Genomics Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Annotation of Fusarium oxysporum Cotton.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-
CC glucose residues with release of alpha-D-glucose.; EC=3.2.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00001657};
CC -!- PATHWAY: Glycan metabolism; N-glycan metabolism.
CC {ECO:0000256|ARBA:ARBA00004833}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
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DR EMBL; KK035215; EXM17470.1; -; Genomic_DNA.
DR AlphaFoldDB; X0MA03; -.
DR HOGENOM; CLU_000631_7_2_1; -.
DR Proteomes; UP000030701; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd14752; GH31_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 2.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR048395; Glyco_hydro_31_C.
DR InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR InterPro; IPR000322; Glyco_hydro_31_TIM.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR PANTHER; PTHR22762:SF54; BCDNA.GH04962; 1.
DR Pfam; PF13802; Gal_mutarotas_2; 1.
DR Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361185};
KW Hydrolase {ECO:0000256|RuleBase:RU361185}.
FT DOMAIN 155..307
FT /note="Glycoside hydrolase family 31 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13802"
FT DOMAIN 349..785
FT /note="Glycoside hydrolase family 31 TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01055"
FT DOMAIN 794..916
FT /note="Glycosyl hydrolase family 31 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21365"
SQ SEQUENCE 1097 AA; 123543 MW; 2A8FD3DD392E9F93 CRC64;
MATPTDPLNF IPADVFFPTV PNFTKPSEIL TVESSASTSS SDPLRYAAHI TLKGEPNTHC
LVQFASPQIW RVRYNPKYTA VSDYDDFNSR TIVRDTFSSL VDDLQQEYRD SEAWNSHPAQ
EGWFWKTSFE QKAPDHWVLT TVEYETKEST GVPNTALHFL ASPFRIVATR KLKALDADPA
FLKTVGIDTV SEYEQIIWQT TDQTFSYQGN PSIGAVNNVV FNIKKPGSAA YLGFGEQGGR
TVIKKPTYLN FFCYDNFNYS KVYGLGALDT REPLYHSTPF FLEMNGTPDR KNVTGVMVDN
YSQVAIDLGK NDSHTISVAT RFNTFDAWIL TADDVPRMIW QYTSIVGRPK LKPRFILGHH
QACYGYSNEG TVNNVVQRYR DSDIPLDGMH LDDKYRTFTN SNKNFPNVGS FLNGLKAKGV
KSCTNITPIL TIRPSDEGPY KALDSFWDPT LANRYSLLVA DKRYLDGLPN NQPLCWRYDG
GLQNLDPNNV NQRERFADYI GAPDYRDDYN FSENYNSGYP FHGGVSYGTN LGTPGFYPDL
NRKAARKKWG EQYQYLFDNG LEFVWQDMTT PAAAKCYGDS LGFPSRLLMT DDSYTNLPKT
KTAIELWSLY SYNLHKATYH GLNNLKGREN KRNFIIGRGS QTGMHRYAGL WTGDNGSSWD
FFRISVAQVL ALGYSGLSIA GVDMGGFTAD PANTLPNPRW CDPELLIRWY SGAFLLPWYR
NHYLQHPEAS SGGCKAFQEP WAYGDILNNF PGPLPPDQAA LYRSVVPVCR YYVQLRYSLL
QVLYDYMFAN LINGLPVARA MLVTDPFDTS LFNSNQGFID NQYLLGHNIL VCPQVEQKAG
RRDVYLPNSD NWYPSNLRVN NQGFGPDPIL KHAAVLQKPA PGGKIVDYDC HIPDAVADPE
QVAYVTPVYI RGGAIIPQLD VRQWVKEGDL NSPTIHVYPG GKTTSYSMYL DDGVSRDSAP
IDLPQHKYKD AAQYTKAKGF YREVKFTQEN TKTNRRITIR HQWDGYDAKA TIGDTYNFAI
WTVQATAPPE SQISVDFEDE NGMTVIDSGL TSTYIVGRGV LTVSVPVHLV PSLKTPQNYT
QGSFADRYLA INVSGLP
//
