ID X0MF15_FUSOX Unreviewed; 987 AA.
AC X0MF15;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Peptidase S8/S53 domain-containing protein {ECO:0000259|Pfam:PF00082};
GN ORFNames=FOTG_12803 {ECO:0000313|EMBL:EXM19185.1};
OS Fusarium oxysporum f. sp. vasinfectum 25433.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1089449 {ECO:0000313|EMBL:EXM19185.1};
RN [1] {ECO:0000313|EMBL:EXM19185.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=25433 {ECO:0000313|EMBL:EXM19185.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J., Gale L.R., Schwartz D.C., Zhou S., Corby-Kistler H., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Goldberg J., Griggs A., Gujja S., Heiman D.,
RA Howarth C., Larson L., Lui A., MacDonald P.J.P., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusarium oxysporum Cotton.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EXM19185.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=25433 {ECO:0000313|EMBL:EXM19185.1};
RG The Broad Institute Genomics Platform;
RA Ma L.-J., Corby-Kistler H., Broz K., Gale L.R., Jonkers W., O'Donnell K.,
RA Ploetz R., Steinberg C., Schwartz D.C., VanEtten H., Zhou S., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Annotation of Fusarium oxysporum Cotton.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
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DR EMBL; JH657965; EXM19185.1; -; Genomic_DNA.
DR AlphaFoldDB; X0MF15; -.
DR HOGENOM; CLU_006016_0_1_1; -.
DR Proteomes; UP000030701; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07491; Peptidases_S8_7; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PANTHER; PTHR43399:SF5; CELL WALL-ASSOCIATED PROTEASE; 1.
DR PANTHER; PTHR43399; SUBTILISIN-RELATED; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SMART; SM00248; ANK; 4.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 888..910
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 217..246
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 686..901
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT REGION 16..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 269..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..381
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 692
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 730
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 887
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 987 AA; 109943 MW; 71BEFC7E4ADC0DCC CRC64;
MSSTRKMSTA IQYCKPNNTE SEYDLVEVEA DAQSKAGDGS SDDSGSEDED GDEEGEKVSV
KDMLTQVLKE IRNGELDLTD SKKLAAFATH RGPDLARQTG DKDQPTALHI MAKEDKKSLP
NLDEKMEPLV KFLCQQKNYL EIKDRSGHTS LFLAIEQRKK IMVQWMCDSH PDISNIISIV
GSKGMNCLHI GINKRIKFLD LLIERAKPEA FAVKDDNGNT PLHLAVDYDN CKREQLEYVK
MMLEKGDRAI FSSTNGDFNK ANLSPYRCHK ESVRKGRKKA AGGAEKPGKE TESVPNRGIS
SSMPPILSAD GSMQPEMRDS MQVDHRTKYG GSIPVQVSVP MASPAPIVIP DSADSKKVPR
DSDASKSKKG KKSGSKSDPV DETIVKGVER LLKLHYLRSR DSTDAMEILY GKYAPSDKEL
SFDLYGMMHP DESLTQKGLA NLLRNIKFED TLQYVWIPRI TVEEPQQSKS RTSMRKQVKP
VPDGAGRSDL VHIFNQLRNK GVETVLRVFV QDSDPDSPSH SDEAIEKALQ GMGVEVWDWN
RTDLCTEVIV TAAPKAREVH LYWSGNNAVL RGWSEAGGLA KLPELGLVKL HIQQGLETSA
RTEDNVNEFQ NRMKLLCPNV EVELEWPNMH RRRTDKTPAR AEEVAEHTTK HEWIHCMTDF
KRLIFEAEAN YPMAPGTKVS ENIEPIQVAI IDDGVDMKDL DYHFTGGRSF CVRSEHRGLL
DPYYMSRTGH GTIMAKNIHL MCPHASLFIL RLEDTPSEDG TKLNITARSA AKAIRAAIVQ
GVQIISMSWT IDPPKDDRER QDLENAVVEA ANANILMFCS ARDKGAHNAP TYPSNATGKI
FTIGAANSSG ASVDYVGNAS ELSYTFPGDK VEVDSGRTPP EIVDGSSVAT ALAAGLAALI
LYCIQVRIFL AKDYEKQKAR EAYKKVKQHE GMVKAFDAIE TTKESNHKFL KVWEVFGKHV
EQKNQKPQGE WLGLVAEVGT RLCYNIY
//
