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Database: UniProt
Entry: X0RBF0_9BACI
LinkDB: X0RBF0_9BACI
Original site: X0RBF0_9BACI 
ID   X0RBF0_9BACI            Unreviewed;       450 AA.
AC   X0RBF0;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   25-OCT-2017, entry version 31.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:GAF66339.1};
GN   ORFNames=BTS2_3239 {ECO:0000313|EMBL:GAF66339.1};
OS   Bacillus sp. TS-2.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1450694 {ECO:0000313|EMBL:GAF66339.1, ECO:0000313|Proteomes:UP000019504};
RN   [1] {ECO:0000313|EMBL:GAF66339.1, ECO:0000313|Proteomes:UP000019504}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TS-2 {ECO:0000313|EMBL:GAF66339.1,
RC   ECO:0000313|Proteomes:UP000019504};
RA   Fujinami S., Takeda K., Onodera T., Satoh K., Sano M., Narumi I.,
RA   Ito M.;
RT   "Draft Genome Sequence of Potassium-Dependent Alkaliphilic Bacillus
RT   sp. Strain TS-2, Isolated from a Jumping Spider.";
RL   Genome Announc. 2:e00458-14(2014).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAF66339.1}.
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DR   EMBL; BAWL01000024; GAF66339.1; -; Genomic_DNA.
DR   RefSeq; WP_045487164.1; NZ_BAWL01000024.1.
DR   EnsemblBacteria; GAF66339; GAF66339; BTS2_3239.
DR   Proteomes; UP000019504; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000019504};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019504}.
FT   DOMAIN      146    274       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      358    427       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     154    161       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   450 AA;  51238 MW;  CA716988CBD1B701 CRC64;
     MENIHDLWER VLAEIEKKVS KPSYETWLKS TKANDIQNDS IIITAPNEFA RDWLEDHYSE
     LTSETIEHIT GSRLTPKFVI PEHKSDNDLF LEPIPKKPPE SQDQSTSSFT KSMLNEKYTF
     NTFVIGSGNR FAHAASLAVA EAPAKAYNPL FIYGGVGLGK THLMHAIGHY VTDHNPNAKV
     VYLSSEKFTN EFINAIRDNK AIDFRNKYRK VDVLLIDDIQ FLAGKESTQE EFFHTFNALH
     EESKQIVISS DRPPKEIPTL EDRLRSRFEW GLITDITPPD LETRIAILRK KAKAENLDIP
     NEVMLYIANQ IDTNIRELEG ALIRVVAYSS LINQDMNADL AAEALKDIIP NAKPKMITIV
     DIQRIVGEHF QVKLEDFKAK KRTKSVAFPR QIAMYLSREL TDSSLPKIGS EFGGRDHTTV
     IHAHEKISKL LASDQDLQKK VQEISEQIRS
//
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