ID   X0S555_9ZZZZ            Unreviewed;       366 AA.
AC   X0S555;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   13-SEP-2023, entry version 28.
DE   RecName: Full=6-phosphogluconate dehydrogenase C-terminal domain-containing protein {ECO:0000259|SMART:SM01350};
DE   Flags: Fragment;
GN   ORFNames=S01H1_00928 {ECO:0000313|EMBL:GAF76193.1};
OS   marine sediment metagenome.
OC   unclassified sequences; metagenomes; ecological metagenomes.
OX   NCBI_TaxID=412755 {ECO:0000313|EMBL:GAF76193.1};
RN   [1] {ECO:0000313|EMBL:GAF76193.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Expedition CK06-06 {ECO:0000313|EMBL:GAF76193.1};
RX   PubMed=24624126; DOI=10.3389/fmicb.2014.00080;
RA   Kawai M., Futagami T., Toyoda A., Takaki Y., Nishi S., Hori S., Arai W.,
RA   Tsubouchi T., Morono Y., Uchiyama I., Ito T., Fujiyama A., Inagaki F.,
RA   Takami H.;
RT   "High frequency of phylogenetically diverse reductive dehalogenase-
RT   homologous genes in deep subseafloor sedimentary metagenomes.";
RL   Front. Microbiol. 5:80-80(2014).
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00008419}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAF76193.1}.
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DR   EMBL; BARS01000363; GAF76193.1; -; Genomic_DNA.
DR   AlphaFoldDB; X0S555; -.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
DR   GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006114; 6PGDH_C.
DR   InterPro; IPR006113; 6PGDH_Gnd/GntZ.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR006184; 6PGdom_BS.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR006183; Pgluconate_DH.
DR   NCBIfam; TIGR00873; gnd; 1.
DR   PANTHER; PTHR11811; 6-PHOSPHOGLUCONATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11811:SF25; 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING; 1.
DR   Pfam; PF00393; 6PGD; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   PRINTS; PR00076; 6PGDHDRGNASE.
DR   SMART; SM01350; 6PGD; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00461; 6PGD; 1.
PE   3: Inferred from homology;
KW   Gluconate utilization {ECO:0000256|ARBA:ARBA00023064}.
FT   DOMAIN          180..366
FT                   /note="6-phosphogluconate dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01350"
FT   NON_TER         366
FT                   /evidence="ECO:0000313|EMBL:GAF76193.1"
SQ   SEQUENCE   366 AA;  39770 MW;  5530C0F5AD4B58CD CRC64;
     MAKADIGLIG LAVMGENLIL NMESKGFTVA CFNRTVSKVD NFINGRAKGK NIIGCHSIEE
     LAENLKTPRK IMLMVKAGAA VDAFIEKLLP HLEDGDIIID GGNSHFPDTI RRTEHVESQG
     KLYIGTGVSG GEEGALLGPS IMPGGSPGAW EHVKPIFQAI CARTAEGEPC CDWVGENGAG
     HFVKMVHNGI EYGDMQMICE TYQMMKEGLG LTNQKMHESF AEWNEGELNS YLIEITRDIL
     DYKDEDGNEV IDLILDTAGQ KGTGKWTAIE ALNLGQPLTL IGEAVFARCL SALKEERVAA
     SKVLSGPKLK FSGDKKAFIS DLRQALYAAK IVSYAQGYQL MRAAAAEHNW NLNYGGIALM
     WRGGCI
//