ID X1TWH3_9ZZZZ Unreviewed; 295 AA.
AC X1TWH3;
DT 14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT 14-MAY-2014, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=HD domain-containing protein {ECO:0000259|PROSITE:PS51831};
DE Flags: Fragment;
GN ORFNames=S12H4_14810 {ECO:0000313|EMBL:GAI84384.1};
OS marine sediment metagenome.
OC unclassified sequences; metagenomes; ecological metagenomes.
OX NCBI_TaxID=412755 {ECO:0000313|EMBL:GAI84384.1};
RN [1] {ECO:0000313|EMBL:GAI84384.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Expedition CK06-06 {ECO:0000313|EMBL:GAI84384.1};
RX PubMed=24624126; DOI=10.3389/fmicb.2014.00080;
RA Kawai M., Futagami T., Toyoda A., Takaki Y., Nishi S., Hori S., Arai W.,
RA Tsubouchi T., Morono Y., Uchiyama I., Ito T., Fujiyama A., Inagaki F.,
RA Takami H.;
RT "High frequency of phylogenetically diverse reductive dehalogenase-
RT homologous genes in deep subseafloor sedimentary metagenomes.";
RL Front. Microbiol. 5:80-80(2014).
CC -!- SIMILARITY: Belongs to the RelA/SpoT family.
CC {ECO:0000256|ARBA:ARBA00007476}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAI84384.1}.
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DR EMBL; BARW01007075; GAI84384.1; -; Genomic_DNA.
DR AlphaFoldDB; X1TWH3; -.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR007685; RelA_SpoT.
DR PANTHER; PTHR21262:SF31; BIFUNCTIONAL (P)PPGPP SYNTHASE_HYDROLASE SPOT; 1.
DR PANTHER; PTHR21262; GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR PROSITE; PS51831; HD; 1.
PE 3: Inferred from homology;
FT DOMAIN 45..144
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT NON_TER 295
FT /evidence="ECO:0000313|EMBL:GAI84384.1"
SQ SEQUENCE 295 AA; 34428 MW; 08D560CF2B0AD8EB CRC64;
MFRTLRGKVN PVNGEQESTE SLLWRAFQLA EISHAGQLRK SGVPYFEHCY NVALLLADWQ
MDPITIAAGL LHDTIEDTAC TSQLIKEQFG AEVSHLVEGV TKLSGIKFRT KAERQAENYM
KLLLSVAKDI RVIIIKFADR LHNMRTIEPL PRVKQRRIAI ETRDVYAPLA HRLGMARIKW
ELEDLALKTL EPEKFEELFR NIRDSLPERE RYIEEFVRPV KKELATYHIR AKVVGRPKST
YSIYGKMQRR RVDFEEIYDL LAVRIITDRP DECYAALGIV HQIYTPIQER FKDFI
//
