GenomeNet

Database: UniProt
Entry: X1WXB1_ACYPI
LinkDB: X1WXB1_ACYPI
Original site: X1WXB1_ACYPI 
ID   X1WXB1_ACYPI            Unreviewed;      5101 AA.
AC   X1WXB1;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   22-NOV-2017, entry version 31.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:ACYPI069453-PA};
GN   Name=LOC100167965 {ECO:0000313|EnsemblMetazoa:ACYPI069453-PA};
OS   Acyrthosiphon pisum (Pea aphid).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha;
OC   Aphidomorpha; Aphidoidea; Aphididae; Macrosiphini; Acyrthosiphon.
OX   NCBI_TaxID=7029 {ECO:0000313|EnsemblMetazoa:ACYPI069453-PA, ECO:0000313|Proteomes:UP000007819};
RN   [1] {ECO:0000313|EnsemblMetazoa:ACYPI069453-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LSR1 {ECO:0000313|EnsemblMetazoa:ACYPI069453-PA};
RA   Jiang H., Abraham K., Ali S., Alsbrooks S.L., Anim B.N., Anosike U.S.,
RA   Attaway T., Bandaranaike D.P., Battles P.K., Bell S.N., Bell A.V.,
RA   Beltran B., Bickham C., Bustamante Y., Caleb T., Canada A.,
RA   Cardenas V., Carter K., Chacko J., Chandrabose M.N., Chavez D.,
RA   Chavez A., Chen L., Chu H.-S., Claassen K.J., Cockrell R., Collins M.,
RA   Cooper J.A., Cree A., Curry S.M., Da Y., Dao M.D., Das B.,
RA   Davila M.-L., Davy-Carroll L., Denson S., Dinh H., Ebong V.E.,
RA   Edwards J.R., Egan A., El-Daye J., Escobedo L., Fernandez S.,
RA   Fernando P.R., Flagg N., Forbes L.D., Fowler R.G., Fu Q., Gabisi R.A.,
RA   Ganer J., Garbino Pronczuk A., Garcia R.M., Garner T., Garrett T.E.,
RA   Gonzalez D.A., Hamid H., Hawkins E.S., Hirani K., Hogues M.E.,
RA   Hollins B., Hsiao C.-H., Jabil R., James M.L., Jhangiani S.N.,
RA   Johnson B., Johnson Q., Joshi V., Kalu J.B., Kam C., Kashfia A.,
RA   Keebler J., Kisamo H., Kovar C.L., Lago L.A., Lai C.-Y., Laidlaw J.,
RA   Lara F., Le T.-K., Lee S.L., Legall F.H., Lemon S.J., Lewis L.R.,
RA   Li B., Liu Y., Liu Y.-S., Lopez J., Lozado R.J., Lu J., Madu R.C.,
RA   Maheshwari M., Maheshwari R., Malloy K., Martinez E., Mathew T.,
RA   Mercado I.C., Mercado C., Meyer B., Montgomery K., Morgan M.B.,
RA   Munidasa M., Nazareth L.V., Nelson J., Ng B.M., Nguyen N.B.,
RA   Nguyen P.Q., Nguyen T., Obregon M., Okwuonu G.O., Onwere C.G.,
RA   Orozco G., Parra A., Patel S., Patil S., Perez A., Perez Y., Pham C.,
RA   Primus E.L., Pu L.-L., Puazo M., Qin X., Quiroz J.B., Reese J.,
RA   Richards S., Rives C.M., Robberts R., Ruiz S.J., Ruiz M.J.,
RA   Santibanez J., Schneider B.W., Sisson I., Smith M., Sodergren E.,
RA   Song X.-Z., Song B.B., Summersgill H., Thelus R., Thornton R.D.,
RA   Trejos Z.Y., Usmani K., Vattathil S., Villasana D., Walker D.L.,
RA   Wang S., Wang K., White C.S., Williams A.C., Williamson J., Wilson K.,
RA   Woghiren I.O., Woodworth J.R., Worley K.C., Wright R.A., Wu W.,
RA   Young L., Zhang L., Zhang J., Zhu Y., Muzny D.M., Weinstock G.,
RA   Gibbs R.A.;
RL   Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:ACYPI069453-PA}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; ABLF02024172; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABLF02024173; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABLF02024174; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_016661950.1; XM_016806461.1.
DR   UniGene; Aps.26992; -.
DR   UniGene; Aps.34943; -.
DR   UniGene; Aps.90704; -.
DR   TCDB; 1.A.3.1.7; the ryanodine-inositol 1,4,5-triphosphate receptor ca(2+) channel (rir-cac) family.
DR   EnsemblMetazoa; ACYPI069453-RA; ACYPI069453-PA; ACYPI069453.
DR   GeneID; 100167965; -.
DR   KEGG; api:100167965; -.
DR   KO; K04962; -.
DR   PhylomeDB; X1WXB1; -.
DR   Proteomes; UP000007819; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   Gene3D; 1.25.10.30; -; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR035910; IP3R_RIH_dom_sf.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 2.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 3.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007819};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007819};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4445   4464       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4627   4647       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4710   4729       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4897   4919       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4973   4996       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       95    149       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      156    201       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      211    265       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      271    319       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      337    397       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      577    802       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1015   1215       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1460   1683       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
SQ   SEQUENCE   5101 AA;  579963 MW;  6500E487FFD8D447 CRC64;
     MADSEGSSEQ DDVSFLRTED MVCLSCTATG ERVCLAAEGF GNRHCYLENI ADKNIPPDLS
     QCVFVIEQAL SVRALQELVT AASSQEGKGG TGSGHRTLLY GNAILLRHQN SDMYLACLST
     SSSNDKLSFD VGLQEHSQGE ACWWTVHPAS KQRSEGEKVR VGDDLILVSV ATERYLHTAK
     ENELSVVNAS FHVTHWSVQP YGTGISRMKY VGYVFGGDVL RFFHGGDECL TIPSSWSDVS
     GQNIVIYEGG SVMSQARSLW RLELARTKWA GGFINWYHPM RIRHLTTGRY LGVNENNELH
     LVCREEATTA SSTFFLRQEK DDQKIILEDK DLEVIGAPII KYGDSTVLVQ HSDTGLWLTY
     KSYETKKKGV GKVEEKQAVL HEEGKMDDGL DFSRSQEEES RTARVIRKCS SLFTQFISGL
     ENLQSNRRSS LFCSFVNLNE MVMCLEDLIN YFAQPEEDME HEEKQNRFRA LRNRQDLFQE
     EGILNLILEA IDKVNIITSQ GFMVSLAGDE SGQSWDVISG YLYQLLAAII KGNHTNCAQF
     ANTNRLNWLF SRLGSQASSE GTGMLDVLHC VLIDSPEALN MMKDEHIKVI ISLLEKHGRD
     PKVLDVLCSL CVGNGVAVRS SQNNICDFLL PGKNLLLQTL LVDHVASVRP NIFVGHVSGS
     AVYRKWYYEV AIDHVEQTTH LNPHIRIGWA NTAGYVPYPG GGEKWGGNGV GDDLYSFGFD
     GSYLWTGGRK SEVMPGTQIS NIKKSDVIGC ALDLTIPIIT FTLNGQLVQG AFRDFNLDGM
     FFPVISCSSK VSCRFLLGGD HGRLKFTPPD EFSPLFETLL PQQILTIDPC FYFGNLNKCV
     LTGPWYVEDD TAFVPNPVDT SMVTLPSYIE NIKDKLAENI HEMWAMNKIE AGWQYGDKRN
     DTRKFHPCLI QFDKLPPAEK RYDSQLAVQT LKTVIALGYH ISIDNPPSRI KTVRLPNEPF
     MQSNGYKPAP LDLSAIILSG KMEELIDQLA ENTHNLWAKE RIQQGWTYGL NEELQMLRSP
     HLVPYSKVDD AIKKANRDTA SETVRTLLVY GYNLDPPTGE TNEATLLTDD NTNRYLTFRT
     YRAEKTYAVS SGKWYFEFEI LTSGPMRVGW ARFTCSPGYQ IGSDENSWAF DGYNEEKIYM
     GTAESFGRQW QVGDVVGVFL DLMDHTISFS MNGELLMDTL GGETTFSEVQ GEGFVPAFTL
     GLGQKAKLTF GQDVNSLKYF TTCGLQEGYE PFCVNMKRPV TYWYTKDQPI FENTDDFSSV
     IDVTRIPAGS DTPPCLKISH NTFETMEKAN WEFLRLSLPV ICLPSFIDEQ EKQRRWQEIR
     IRQHRLLSQS EHATPAHIEQ IMKSGFSMSD IKGLHRGYSD DPVENDEMMP NATPLPPRGK
     NQPPPPRPPR KGSLSRHDDL TIENEGKLNR SSSELNFNIY NHQNGDGQDI NKDDKKKRGR
     SPFRFFSRKK EGPSDNPKRA KTPDPVRNVD RSRNAAHRPN TLNERVTPQI RVSQMDLKLV
     PPAIPDRPGG PKAMSFTPTS AGIEFVGNEI FDLECLKLIN EYYYGVRIFP GQDPTHVYVG
     WVTTQYHLHT KDFSQNHVRK STVTIVDEHN RILESIDRQS CYMVRSDELY NEVTNDSSGK
     GASQGMAIGC FIDIATGMMS FTCEGKETSF KFKMEPDIKL FPAIFVEASS KEILQIELGR
     TSTTLPLSAA VLQNSERHVL PQFPPRLKVQ CLRPHQWARV PNDSLHIHTL KLSDIRGWSI
     LCEDPVSMIA LHIPEEDRCI DILELIEMEK LLSFHAHTLT LYAAVCYQAN YRAAHILCTH
     VNQKQLLYAI CSEYMSGPLR QGFYDLLIAL HLESHATTME VCKNEYIIPL GHELTTLYDD
     PQMGHSLRSL QTESVRPQMK MTEISDVIDN VRNLYSPYFP LQVVREYVMA ALEEAVLVNQ
     VHNRDPIGGS NENLFLPLLK LVDRLLLVGM LRDEDVEKLL IMINPETWDP EFQKDGPDEH
     RKGLLHMKMA EGAKLQMCYL LHHLCDIQLR HRVESIISFS YQFVNDIQID QLRRYNEIKQ
     SDLPSAVAAK KTREFRCPPR EQMNAILGFK NLDSDDKENC LIGDDLRERM NEFNEKLMKQ
     ISLVALQESE DDKSDLNNLN NEGKIKQFYN FINAVKDEGN EDGLNEQEKK IPEEIFRKVL
     ISTIVSWAEE TQIETPKLVR EMFSLLVRQY DSVGELIRAL EKTYVINFKT KEDVAQMWVG
     LSQIRSLLPV QMSQEEEELM RERLWKLVNN HTFFQHPDLI RVLRMHENVM AVMMNTLGRR
     AQAQSQPGGT PVTGQDGEIV PKEKDTSHEM VVACCRFLCY FCRTSRQNQK AMFDHFSFLL
     ENSNILLSRP SLRGSTPLDV AYSSLMENTE LALALREHYL EKIAIYLSRC GLQSNSELIE
     KGYPDLGWDP VEGERYLDFL RFCVWVNGES VEENANLVIR LLIRRPECLG PALRGEGEGL
     LRAIIDANKM SERITERRKF LEESGNQENI QLDHPLPESD EDEDYIDTGA AILNFYCTLV
     DLLGRCAPDS SVISLGKNES LRARAILRSL VPLEDLHGVL SLRFTLQNPA AGQDRPKSDM
     PSGLIPGHKQ SVVLFLERVY GIEMQELFFT LLEEAFLPDL RTATMLDRND GLESDMALAM
     NRYIGNSVLP LLIGHSKFYS ESDNYANLLD ATLHTVYRLS KNRMLTKGQR EAVSDFLVAL
     TSQMQPSMLL KLLRKLTVDV SNLSEYTTVA LRLLTLHYDR CAKYYGSTGG QGIYGASSDE
     EKRLTMMLFS NIFDSLSKMD YDPELFGKAL PCLSAIGCAL PPDYSLSKNH DDEWYGSKQN
     IQGPSDGPYN PQPINTNSIV LDNDLNSIVH KFSEHYHDAW ANRKLENGWV YGEQFNDVNK
     SHPRLKPYMM LSEYEKELYK EPVRESLKAL LAIGWSIEHS ENDAPLNNRG SVRRQSKSNE
     NVTPFDYHPN PIDMTNLTLT REMQNMAERL AENSHDIWAK KKKEEVMLCG GGIHNQLVPY
     DLLTDKEKKK DRERSQEFLK YLQYQGYKLH RPNRNGGPSE AEQLAAASTG ELRFSYSLLE
     KLIHYIDRAS INMKLLKPSG TFSRRSSFKI CTRDIKFFSK VVLPLVEKYF STHRNYFITV
     ATASSVLGAA SLKEKEMVAS LFCKLANLLR SKLMAFGADV RITVRCLQVL VKAIDAKSLV
     KNCPEFIRTS MLTFFHNIAD DLEHTIQNLH DSRYCYLRGT HLKTSTSLFY VNDVILPVLS
     SLFDHLAAYE YGNELLLNEI QVAAYKMLSS LYTLGTDTSL THDRKYLKVQ LERHRPAFGS
     CLGAFSSTFP VAFLEPHLNK HNQYSLLNRF ADSSLEAQDI MSRMEGTMPT LETVLNEVDQ
     FIESEKTYAD APHIIDVILP LLCSYLPYWW AQGPDNVALT TGNHVTMVTS EHMNCLLKNV
     LKLIKKNIGN DNAPWMTQIA AYTQQIIINS SEELLKDPFL PLAERVKKRT ETLYHKEESL
     RGFIKSSTDD TSQIEAQIQE DWQLVVRDIY AFYPLLIKYV DLQRNHWLRN NISNAEDLYN
     HVSEIFNIWS KSQYFLREEQ NFISANEIDN MILIMPTATR RSAVISETSL GGSTGKKKKK
     HRDKKRDKEK EIQASLMVAC LKRLLPVGLN LFAGREQELV QHCKDRFLKR MPDYDVIQFV
     KIQLTLPDKL DPADEMSWQH YLYSKLGSKK GTTEIKPQQV DEVADRIVAM AKVLYGLHMI
     DHPQLQSKAI YRSVVSTQRK RAVIACFRQL SLHALTRHRA VNIFVRSFYE LWLQDENIGQ
     EVMIEDLTQS FEEAELKKRD KEEEEGMADP LNQMVTTFCR GAMTERSGAL QEDPLYMSYA
     DILAKSCGEE EEEGNNEEEG STGNGEEEGG ASIHEQEMEK QKLLFHQARL ANRGVAEMVL
     LHISACKGIP SEMVMKTLQL GIAVLRGGNL EIQMGMLNHL KEKKDVGFFT SVAGLMNSCS
     VLDLDAFERN TKAEGLGVGS EGAAGEKNMH DAEFTCTLFR FIQLTCEGHN LEWQNYLRTQ
     AGNTTTVNVV ICTVDYLLRL QESIMDFYWH YSSKELIDPA GKANFFKAIG VASQVFNTLS
     EVIQGPCTQN QQALAHSRLW DAVGGFLFLF SHMQDKLSKH SSQVDLLKEL LNLQKDMITM
     MLSMLEGNVV NGTIGKQMVD TLVESASNVE LILKYFDMFL KLKDLTSSAS FTEIDPNNDG
     WVHPKDFKEK MEQQKSYTAE EIEFMLQCCE SNHDGKIDYI GFTDQFHEPS KEIGFNLAVL
     LTNLSEHMPN EPRLTRFLET ASSVLNYFQP FLGRIEILGG SKRIERVYFE IKESNIEQWL
     KPQIRESKRA FFYSIVTEGG DKEKLEAFVN FCEDAIFEMQ HASGLMAVDD GSGIGGGKSR
     KTAYTYMADD EENKTAKDPI RRGIQAIKYG FHLLFFVLSP TNIKNKINEI QQMSVIELIT
     SFFKLWFYLI FYTGYSGVYV LRYISRILMQ LMSGTQSEET TVEVVEEKSG SFRMLPALPS
     SGMDEPPSTL TDGNNMRKNS GSPDSKHLKS NSVGDDKDET SAENHEKEDG VDGSEQQASF
     VDLLVGESAR KDSIAGPEVL AQQQAVMAAV EAEIKQKNSV ENPSAFSTID INAYTHRALS
     FLARNFYNLK YVALVLAFCI NFILLFYKVT TLADDLSDDG DVKEFALGSA GISNDDMDDS
     NSTEIADDEG VLELVHVNED FFYMAHVMRL AALLHSLASL AMLIAYYHLK VPLAIFKREK
     EIARRLEFDG LYIVEQPEDD DIKSHWDKLV ISAKSFPVNY WDKFAKKKVR QKYSETYDFD
     SISNLLGMEK TSFSTQENEE RTGLINFVIN IDWRYQVWKA GVTITDNAFL YSLWYFTFSI
     LGNFNNFFFA AHLLDVAVGF KTLRTILQSV THNGKQLVLT VLLLTIIVYI YTVIAFNFFR
     KFYVQEEDDE VDKKCHDMLT CFVFHLYKGV RAGGGIGDEI GSPDGDDYEV YRIMFDITFF
     FFVIIILLAI IQGLIIDAFG ELRDQLESVK EDMESNCFIC GIGKDYFDKV PHGFDTHVQE
     EHNLANYMFF LMHLINKPDT EYTGQETYVW NMYQQRCWDF FPVGDCFRKQ YEEELGGGGG
     V
//
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