ID X2C2F8_9TELE Unreviewed; 287 AA.
AC X2C2F8;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Polycystic kidney disease 1 {ECO:0000313|EMBL:AGF35111.1};
DE Flags: Fragment;
GN Name=Pkd1 {ECO:0000313|EMBL:AGF35111.1};
OS Liopropoma fasciatum (wrasse ass bass).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Serranoidei; Serranidae; Epinephelinae;
OC Liopropomini; Liopropoma.
OX NCBI_TaxID=546525 {ECO:0000313|EMBL:AGF35111.1};
RN [1] {ECO:0000313|EMBL:AGF35111.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=2 {ECO:0000313|EMBL:AGF35111.1};
RX PubMed=25093850;
RA Schoelinck C., Hinsinger D.D., Dettai A., Cruaud C., Justine J.L.;
RT "A phylogenetic re-analysis of groupers with applications for ciguatera
RT fish poisoning.";
RL PLoS ONE 9:E98198-E98198(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JX093928; AGF35111.1; -; Genomic_DNA.
DR AlphaFoldDB; X2C2F8; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR46730; POLYCYSTIN-1; 1.
DR PANTHER; PTHR46730:SF3; POLYCYSTIN-1; 1.
DR Pfam; PF00801; PKD; 2.
DR Pfam; PF18911; PKD_4; 1.
DR SMART; SM00089; PKD; 3.
DR SUPFAM; SSF49299; PKD domain; 3.
DR PROSITE; PS50093; PKD; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 14..87
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 109..154
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT DOMAIN 183..238
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AGF35111.1"
FT NON_TER 287
FT /evidence="ECO:0000313|EMBL:AGF35111.1"
SQ SEQUENCE 287 AA; 31895 MW; 0154639D90A19565 CRC64;
TRVDIQTEPR LLLAGKSADF EAHPLPSPYG IHYDWHFGDG STPLQGRRVA HTFAQSGFFN
VCVSVNNTIS SMEACAEMFV YEEIEDLTAE SSSPTELHSP TTVWARLASG NNITWTFSMG
DGTVYPTSKP HVSHSYVKDG NYTVNVTAAN AVSSGWTILP VQVFVFQVVR MEPSGCVQER
TPVNFQAWVS GNASAHLYEW SFGDGSPNET HHGNPRVSHT YWTSGNYHLS LLLSSGINKD
TKANFFNWVC VQPALTNISL TLEKSHYAVG EEIRFQVRAE PEFNYSY
//
