ID X4R6B6_POVBK Unreviewed; 179 AA.
AC X4R6B6;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Large T antigen {ECO:0000313|EMBL:AHU87378.1};
DE Flags: Fragment;
GN Name=large T antigen {ECO:0000313|EMBL:AHU87378.1};
OS BK polyomavirus (BKPyV) (Human polyomavirus 1).
OC Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes;
OC Sepolyvirales; Polyomaviridae; Betapolyomavirus.
OX NCBI_TaxID=1891762 {ECO:0000313|EMBL:AHU87378.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1] {ECO:0000313|EMBL:AHU87378.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Donor218 {ECO:0000313|EMBL:AHU87378.1};
RX PubMed=24361208; DOI=10.1016/j.jcv.2013.11.009;
RA Schmitt C., Raggub L., Linnenweber-Held S., Adams O., Schwarz A., Heim A.;
RT "Donor origin of BKV replication after kidney transplantation.";
RL J. Clin. Virol. 59:120-125(2014).
CC -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000256|ARBA:ARBA00004147}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KF468341; AHU87378.1; -; Genomic_DNA.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR014015; Helicase_SF3_DNA-vir.
DR InterPro; IPR010932; Lg_T_Ag_Polyomavir_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF06431; Polyoma_lg_T_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51206; SF3_HELICASE_1; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Early protein {ECO:0000256|ARBA:ARBA00022518};
KW Host nucleus {ECO:0000256|ARBA:ARBA00022562};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 1..153
FT /note="SF3 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51206"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AHU87378.1"
FT NON_TER 179
FT /evidence="ECO:0000313|EMBL:AHU87378.1"
SQ SEQUENCE 179 AA; 20389 MW; 8BBC0186441F7B22 CRC64;
FLHCIVFNVP KRRYWLFKGP IDSGKTTLAA GLLDLCGGKA LNVNLPMERL TFELGVAIDQ
YMVVFEDVKG TGAESKDLPS GHGINNLDSL RDYLDGSVKV NLEKKHLNKR TQIFPPGLVT
MNEYPVPKTL QARFVRQIDF RPKIYLRKSL QNSEFLLEKR ILQSGMTLLL LLIWFRPVA
//
