ID X5CZD9_PTEGI Unreviewed; 239 AA.
AC X5CZD9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};
DE Flags: Fragment;
GN Name=OR2 {ECO:0000313|EMBL:AHW55411.1};
OS Pteropus giganteus (Indian flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=143291 {ECO:0000313|EMBL:AHW55411.1};
RN [1] {ECO:0000313|EMBL:AHW55411.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Pgi_38 {ECO:0000313|EMBL:AHW55411.1};
RX PubMed=24441035; DOI=10.1093/molbev/msu043;
RA Hayden S., Bekaert M., Goodbla A., Murphy W.J., Davalos L.M., Teeling E.C.;
RT "A cluster of olfactory receptor genes linked to frugivory in bats.";
RL Mol. Biol. Evol. 31:917-927(2014).
CC -!- FUNCTION: Putative odorant or sperm cell receptor.
CC {ECO:0000256|ARBA:ARBA00003929}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU363047}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363047}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR EMBL; KC931289; AHW55411.1; -; Genomic_DNA.
DR AlphaFoldDB; X5CZD9; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PANTHER; PTHR26453; OLFACTORY RECEPTOR; 1.
DR PANTHER; PTHR26453:SF718; OLFACTORY RECEPTOR FAMILY 2 SUBFAMILY A MEMBER 58; 1.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU363047};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363047};
KW Olfaction {ECO:0000256|ARBA:ARBA00022725, ECO:0000256|RuleBase:RU363047};
KW Receptor {ECO:0000256|RuleBase:RU000688, ECO:0000313|EMBL:AHW55411.1};
KW Sensory transduction {ECO:0000256|RuleBase:RU363047};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363047}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..239
FT /note="Olfactory receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004953618"
FT TRANSMEM 43..65
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 85..107
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 142..161
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 182..206
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT TRANSMEM 218..237
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363047"
FT DOMAIN 1..235
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AHW55411.1"
FT NON_TER 239
FT /evidence="ECO:0000313|EMBL:AHW55411.1"
SQ SEQUENCE 239 AA; 27227 MW; 55FF276E20909A94 CRC64;
HQPMYLLLSH LAVIDIAYAS SNLPNMLENL VKHKKTISFV SCTLQMYCFL IFADTECLIL
MVMSYDRFVA ICHPLQYTAI MNWRVCTVLA IACWACGFSL SLVHLILFLR LPFCGPQAIN
HFFCEILSVL NVACGDTWIN KIFLLAACMF ILVGPLSLML VSYIRILQAI LKIRSMEGRR
KAFSTCSSHL CVVGFYFGIA MMVYLVPENS DREEHQKILA LFYTLFNPLL NPVIYGIRT
//
