ID X5DYS7_9BACT Unreviewed; 133 AA.
AC X5DYS7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Putative nickel-responsive regulator {ECO:0000256|HAMAP-Rule:MF_00476};
GN ORFNames=SAMN05444285_1034 {ECO:0000313|EMBL:SES87686.1};
OS Draconibacterium orientale.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Prolixibacteraceae;
OC Draconibacterium.
OX NCBI_TaxID=1168034 {ECO:0000313|EMBL:SES87686.1, ECO:0000313|Proteomes:UP000181981};
RN [1] {ECO:0000313|EMBL:SES87686.1, ECO:0000313|Proteomes:UP000181981}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25947 {ECO:0000313|EMBL:SES87686.1,
RC ECO:0000313|Proteomes:UP000181981};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcriptional regulator. {ECO:0000256|HAMAP-Rule:MF_00476}.
CC -!- COFACTOR:
CC Name=Ni(2+); Xref=ChEBI:CHEBI:49786;
CC Evidence={ECO:0000256|ARBA:ARBA00001967};
CC -!- SIMILARITY: Belongs to the transcriptional regulatory CopG/NikR family.
CC {ECO:0000256|ARBA:ARBA00008478, ECO:0000256|HAMAP-Rule:MF_00476}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_00476}.
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DR EMBL; FOHT01000003; SES87686.1; -; Genomic_DNA.
DR RefSeq; WP_038557093.1; NZ_FOHT01000003.1.
DR AlphaFoldDB; X5DYS7; -.
DR STRING; 1168034.FH5T_07260; -.
DR GeneID; 78098463; -.
DR eggNOG; COG0864; Bacteria.
DR HOGENOM; CLU_113319_1_1_10; -.
DR OrthoDB; 9806294at2; -.
DR Proteomes; UP000181981; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016151; F:nickel cation binding; IEA:UniProtKB-UniRule.
DR GO; GO:0010045; P:response to nickel cation; IEA:InterPro.
DR CDD; cd22231; RHH_NikR_HicB-like; 1.
DR Gene3D; 3.30.70.1150; ACT-like. Chain A, domain 2; 1.
DR Gene3D; 1.10.1220.10; Met repressor-like; 1.
DR HAMAP; MF_00476; NikR; 1.
DR InterPro; IPR027271; Acetolactate_synth/TF_NikR_C.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR013321; Arc_rbn_hlx_hlx.
DR InterPro; IPR002145; CopG.
DR InterPro; IPR022988; Ni_resp_reg_NikR.
DR InterPro; IPR010985; Ribbon_hlx_hlx.
DR InterPro; IPR014864; TF_NikR_Ni-bd_C.
DR PANTHER; PTHR34719; NICKEL-RESPONSIVE REGULATOR; 1.
DR PANTHER; PTHR34719:SF2; NICKEL-RESPONSIVE REGULATOR; 1.
DR Pfam; PF08753; NikR_C; 1.
DR Pfam; PF01402; RHH_1; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF47598; Ribbon-helix-helix; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00476}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nickel {ECO:0000256|ARBA:ARBA00022596};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00476};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_00476}.
FT DOMAIN 5..40
FT /note="Ribbon-helix-helix protein CopG"
FT /evidence="ECO:0000259|Pfam:PF01402"
FT DOMAIN 54..129
FT /note="Transcription factor NikR nickel binding C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08753"
SQ SEQUENCE 133 AA; 15236 MW; 29D8E8FD6182224F CRC64;
MAVSRFGVSL DEELLEALDK YVEDNAFANR SRAIRHLIEK NLVEEKWKCD NIVAGAVIIV
FNHEKKDILK KSAEIQYEHK EFILSSQGFY LNELNYMEII AVKGPSRKLT EISEQLISLK
GIQHGKLVMS KAE
//
