ID X5J792_9BACT Unreviewed; 1181 AA.
AC X5J792;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Sodium:solute symporter family protein {ECO:0000313|EMBL:CDG49708.1};
GN ORFNames=CHV_a0395 {ECO:0000313|EMBL:CDG49708.1};
OS Cardinium endosymbiont cBtQ1 of Bemisia tabaci.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Amoebophilaceae;
OC Cardinium.
OX NCBI_TaxID=1354314 {ECO:0000313|EMBL:CDG49708.1, ECO:0000313|Proteomes:UP000024482};
RN [1] {ECO:0000313|EMBL:CDG49708.1, ECO:0000313|Proteomes:UP000024482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cBtQ1 {ECO:0000313|Proteomes:UP000024482};
RX DOI=10.1093/gbe/evu077;
RA Santos-Garcia D., Rollat-Farnier P.A., Beitia F., Zchori-Fein E., Vavre F.,
RA Mouton L., Moya A., Latorre A., Silva F.J.;
RT "The genome of Cardinium cBtQ1 provides insights into genome reduction,
RT symbiont motility and its settlement in Bemisia tabaci.";
RL Genome Biol. Evol. Evol.0:0-0(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-proline(in) + Na(+)(in) = L-proline(out) + Na(+)(out);
CC Xref=Rhea:RHEA:28967, ChEBI:CHEBI:29101, ChEBI:CHEBI:60039;
CC Evidence={ECO:0000256|ARBA:ARBA00033708};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21)
CC family. {ECO:0000256|ARBA:ARBA00006434}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDG49708.1}.
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DR EMBL; CBQZ010000001; CDG49708.1; -; Genomic_DNA.
DR AlphaFoldDB; X5J792; -.
DR STRING; 1354314.CHV_a0395; -.
DR eggNOG; COG0317; Bacteria.
DR eggNOG; COG0591; Bacteria.
DR Proteomes; UP000024482; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd10322; SLC5sbd; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 1.20.1730.10; Sodium/glucose cotransporter; 1.
DR InterPro; IPR038377; Na/Glc_symporter_sf.
DR InterPro; IPR001734; Na/solute_symporter.
DR PANTHER; PTHR48086; SODIUM/PROLINE SYMPORTER-RELATED; 1.
DR PANTHER; PTHR48086:SF3; SODIUM_PROLINE SYMPORTER; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF00474; SSF; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024482};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 565..585
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 605..627
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 639..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 1181 AA; 132130 MW; 62C86A8F16A5214D CRC64;
MIYFNMPLYI VAVFLGLTFL MGIYFSRKRT TFREYAIGNK QFATATLVAT VLATFFGGGG
LVRNIECVYD LGLWWIMYQL IKNSCHLWIF SRLTLRMGSF MHHLSMQETI GHIYGKYPKV
MAILGGICFS IFVIITQIKV MSLAINMCIE LNNSYVIPIV CTSLLIFYST FGGIRAITYT
DVLQFITFAI IIPFLAWLMF VQVGKPVAEI IPIIQNYPKF QCASLFKDKQ LVSLLLLILT
GIVTLIDPTV IQRVYMSSSP IQAKKVFAYA NIFEIIITFF IILIAIFVFT GAPSLPKEAV
FGYIVTHVPS FFKGLLTISL LAMTMSTADS YLNACAIMVS HDVLKTVQNK KEISDADQLK
IARWTTLTVG LIAMVLAFHY KDLLQLLFLA YAFYIPIVTA PFILAIFGFR GTSRTALIGM
TTGACTILAW NKWVKPSTGM DGSFVSMLAN GLAMVAAHYL FKQPEGAGWS KPDDEFQQMR
QAQARKRAER RAAIKMAWAN RKVTLGKLAP GDATLRLMGL YMVVTSIVDY WFMQPTGISW
AISQVCIGAL FIASKTFFSK MLPNWSIGLG ALTALTIYLP LDLLWHCWYA LDPTFTASLS
LTHCAIILSI LPLYLGTKVV AATTLLMAST AIGCALPELV ALLPLCIAIL FIFAIIIYFK
VRLSRSTTKI LYFEKREQLK EAEKLKASLY DAAIIPAASA GQCKGYGAIL GQVIRKMEES
ISFLDQNTPL YKQDFQSIIH RLYDWVAYFN RREKAKKHAL LQPTKIDIDQ LIHKVEFALS
QEMADPPRLL VEKINDMGPL CPHIICDINQ VVYLLTQVVL RVGSLANAPI IRLQLQTTAL
QFKQADAVES HYPLSILFEA TAWVISKAAT PFEALPKVKK CYDDRVDPIG PQVQQQCPPS
IDLQQATIST IVAAHYGYTE IALHRIPPTI LLVLPTDVTE ILNHMTAGLP IDALAKEGPI
SPKEEADSMM ALMQFHDYVC KSAYENDPID LVTLSGLLLL LRQRFGSKRH GSGQLFYVRA
VGIATLVVEW AFHSPKVIYA SLLYDLVRHT CLPLSYVREH YNLGVYGFVW NVVNTDKREA
LDHPSLLYVQ NRLQAAIKEE HVQLSVLFIK LAERLYDLRH AAGYVHLPEV HHMAQETLTI
DVQLANKYLN PEIGAALEEA AKAALAICAN HPSEKNHHTV G
//
